Evidence map›Paper›PMID 32365578›Full record

ReviewBioengineering (Basel, Switzerland)2020

Nanocellulose-Based Inks for 3D Bioprinting: Key Aspects in Research Development and Challenging Perspectives in Applications-A Mini Review.

Xiaoju Wang, Qingbo Wang, Chunlin Xu

Abstract readReview
In one paragraph

Review in Bioengineering (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Trends in the Treatment of Chronic Wounds.Current medicinal chemistry · 2025
    Review
  9. Scaffolds Bioink for Three-Dimensional (3D) Bioprinting.Food science of animal resources · 2025
    Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. Review
  16. Three-Dimensional Printed Cellulose for Wound Dressing Applications.3D printing and additive manufacturing · 2023
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Xiaoju WangLaboratory of Natural Materials Technology, Åbo Akademi University, Porthaninkatu 3-5, 20500 Turku, Finland.ORCID 0000-0002-1728-4164
Qingbo WangLaboratory of Natural Materials Technology, Åbo Akademi University, Porthaninkatu 3-5, 20500 Turku, Finland.
Chunlin XuLaboratory of Natural Materials Technology, Åbo Akademi University, Porthaninkatu 3-5, 20500 Turku, Finland.

Funding

Academy of Finland 298325Jane ja Aatos Erkon Säätiö Xiaoju Wang
6 · The paper itself

Abstract

Nanocelluloses have emerged as a catalogue of renewable nanomaterials for bioink formulation in service of 3D bioprinting, thanks to their structural similarity to extracellular matrices and excellent biocompatibility of supporting crucial cellular activities. From a material scientist's viewpoint, this mini-review presents the key research aspects of the development of the nanocellulose-based bioinks in 3D (bio)printing. The nanomaterial properties of various types of nanocelluloses, including bacterial nanocellulose, cellulose nanofibers, and cellulose nanocrystals, are reviewed with respect to their origins and preparation methods. Different cross-linking strategies to integrate into multicomponent nanocellulose-based bioinks are discussed in terms of regulating ink fidelity in direct ink writing as well as tuning the mechanical stiffness as a bioactive cue in the printed hydrogel construct. Furthermore, the impact of surface charge and functional groups on nanocellulose surface on the crucial cellular activities (e.g., cell survival, attachment, and proliferation) is discussed with the cell-matrix interactions in focus. Aiming at a sustainable and cost-effective alternative for end-users in biomedical and pharmaceutical fields, challenging aspects such as biodegradability and potential nanotoxicity of nanocelluloses call for more fundamental comprehension of the cell-matrix interactions and further validation in in vivo models.

Indexed as

3D bioprintingbacterial nanocellulosebioinkcellulose nanocrystalscellulose nanofibrilshydrogelnanocellulose

Identifiers

PMID32365578
PMCPMC7355978

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.