Evidence map›Paper›PMID 32365569›Full record

ArticleBiomolecules2020

Functional Implications of Cathelicidin Antimicrobial Protein in Breast Cancer and Tumor-Associated Macrophage Microenvironment.

Jiawei Chen, Vivian Yvonne Shin, John Chi-Wang Ho, Man-Ting Siu, Isabella Wai-Yin Cheuk, Ava Kwong

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Review
  3. TIM3Cancer cell · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. A Novel Immune-Related Signature to Predict Prognosis and Immune Infiltration of Cervical Cancer.Medical science monitor : international medical journal of experimental and clinical research · 2023
    Article
  8. Article
  9. Review
  10. Neutrophils in cancer carcinogenesis and metastasis.Journal of hematology & oncology · 2021
    Review
  11. Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Jiawei ChenDepartment of Surgery, The University of Hong Kong, Pokfulam 999077, Hong Kong.ORCID 0000-0002-0895-9027
Vivian Yvonne ShinDepartment of Surgery, The University of Hong Kong, Pokfulam 999077, Hong Kong.
John Chi-Wang HoDepartment of Surgery, The University of Hong Kong, Pokfulam 999077, Hong Kong.
Man-Ting SiuDepartment of Surgery, The University of Hong Kong, Pokfulam 999077, Hong Kong.
Isabella Wai-Yin CheukDepartment of Surgery, The University of Hong Kong, Pokfulam 999077, Hong Kong.
Ava KwongDepartment of Surgery, The University of Hong Kong, Pokfulam 999077, Hong Kong.
University of Hong Kong · HKHong Kong Sanatorium and Hospital · HK

Funding

Dr Ellen Li Charitable Foundation naHong Kong Hereditary Breast Cancer Family Registry naKerry Kuok Foundation naSeed Fund for Basic Research 201611159186Small Project Funding 201409176192
6 · The paper itself

Abstract

It is well-established that tumor-associated macrophages (TAMs) play an important role in breast cancer development. Accumulating evidence suggested that human cathelicidin antimicrobial protein (

Indexed as

Tumor MicroenvironmentAdultAnimalsAntimicrobial Cationic PeptidesBreast NeoplasmsCathelicidinsCell MovementCell ProliferationFemaleHumansMCF-7 CellsMiceMice, Inbred NODMice, SCIDMiddle AgedTHP-1 CellsAntimicrobial Cationic PeptidesCathelicidinsbreast cancercathelicidin antimicrobiatumor associated macrophagetumor microenvironment

Identifiers

PMID32365569
PMCPMC7277779
OpenAlexW3021966881

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.