Evidence map›Paper›PMID 32365547›Full record

ArticleCells2020

Mouse Gonad Development in the Absence of the Pro-Ovary Factor WNT4 and the Pro-Testis Factor SOX9.

Furong Tang, Nainoa Richardson, Audrey Albina, Marie-Christine Chaboissier, Aitana Perea-Gomez

Open access · goldAbstract read
In one paragraph

Article in Cells, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 27 citations in OpenAlex.

  1. Spatiotemporally primed coelomic epithelium and supporting-like cells establish the dual origin of granulosa cells.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. How relevant is the mouse model for understanding human sex determination?International journal of biological sciences · 2025
    Article
  7. Article
  8. Article
  9. Review
  10. Current progress onFrontiers in cell and developmental biology · 2023
    Review
  11. Article
  12. Article
  13. Becoming female: Ovarian differentiation from an evolutionary perspective.Frontiers in cell and developmental biology · 2022
    Review
  14. Review
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Furong TangUniversité Côte d'Azur, CNRS, Inserm, Institut de Biologie Valrose (iBV), 06108 Nice, France.ORCID 0000-0001-7546-7500
Nainoa RichardsonUniversité Côte d'Azur, CNRS, Inserm, Institut de Biologie Valrose (iBV), 06108 Nice, France.
Audrey AlbinaUniversité Côte d'Azur, CNRS, Inserm, Institut de Biologie Valrose (iBV), 06108 Nice, France.
Marie-Christine ChaboissierUniversité Côte d'Azur, CNRS, Inserm, Institut de Biologie Valrose (iBV), 06108 Nice, France.ORCID 0000-0003-0934-8217
Aitana Perea-GomezUniversité Côte d'Azur, CNRS, Inserm, Institut de Biologie Valrose (iBV), 06108 Nice, France.
Centre National de la Recherche Scientifique · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The transcription factors SRY and SOX9 and RSPO1/WNT4/β-Catenin signaling act as antagonistic pathways to drive testis and ovary development respectively, from a common gonadal primordium in mouse embryos. In this work, we took advantage of a double knockout mouse model to study gonadal development when

Indexed as

AnimalsCell DifferentiationFemaleGene Expression Regulation, DevelopmentalGonadsGranulosa CellsMaleMice, KnockoutOvarySOX9 Transcription FactorTestisWnt4 ProteinSox9 protein, mouseSOX9 Transcription FactorWnt4 ProteinWnt4 protein, mousegonad developmentovotestissex determinationSOX9WNT signaling

Identifiers

PMID32365547
PMCPMC7291083
OpenAlexW3021509536

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.