Evidence map›Paper›PMID 32365533›Full record

ArticleJournal of clinical medicine2020

The Effect of a Virtual Reality-Based Intervention Program on Cognition in Older Adults with Mild Cognitive Impairment: A Randomized Control Trial.

Ngeemasara Thapa, Hye Jin Park, Ja-Gyeong Yang, Haeun Son, Minwoo Jang, Jihyeon Lee, Seung Wan Kang, Kyung Won Park, Hyuntae Park

Registry-linked trialOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05265182 (Developing an Immersive Gamification Technology System), which is not on this map. Cited by 97 papers, 22 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
97citing papers in PubMed, 22 pooled it
16.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05265182 nacompletednot on this mapstarted 2022, after this paper: background citation

Developing an Immersive Gamification Technology System (ImGTS) for the Management of Patients With Behavioral and Psychological Symptoms of Dementia (Phase 1 Trial)

TypeinterventionalSponsorAugmented eXperience E-health LaboratoryRan2022 to 2022Enrolled30ConditionsDementia AlzheimersArmsvirtual reality
3 · Its place in the literature

Who cites it

97 citing papers in PubMed, 22 syntheses or guidelines pooled it, 225 citations in OpenAlex.

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37 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Ngeemasara ThapaDepartment of Health Sciences, Graduate School, Dong-A University, Busan 49315, Korea.ORCID 0000-0001-9394-2539
Hye Jin ParkDepartment of Health Sciences, Graduate School, Dong-A University, Busan 49315, Korea.
Ja-Gyeong YangDepartment of Health Sciences, Graduate School, Dong-A University, Busan 49315, Korea.
Haeun SonDepartment of Health Sciences, Graduate School, Dong-A University, Busan 49315, Korea.
Minwoo JangDepartment of Health Sciences, Graduate School, Dong-A University, Busan 49315, Korea.
Jihyeon LeeDepartment of Health Sciences, Graduate School, Dong-A University, Busan 49315, Korea.
Seung Wan KangData Center for Korean EEG, College of Nursing, Seoul National University, Seoul 03080, Korea.
Kyung Won ParkDepartment of Neurology, Dong-A University College of Medicine, Busan 49201, Korea.ORCID 0000-0002-6788-5267
Hyuntae ParkDepartment of Health Sciences, Graduate School, Dong-A University, Busan 49315, Korea.ORCID 0000-0002-1976-0005
Dong-A University · KRSeoul National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to investigate the association between a virtual reality (VR) intervention program and cognitive, brain and physical functions in high-risk older adults. In a randomized controlled trial, we enrolled 68 individuals with mild cognitive impairment (MCI). The MCI diagnosis was based on medical evaluations through a clinical interview conducted by a dementia specialist. Cognitive assessments were performed by neuropsychologists according to standardized methods, including the Mini-Mental State Examination (MMSE) and frontal cognitive function: trail making test (TMT) A & B, and symbol digit substitute test (SDST). Resting state electroencephalogram (EEG) was measured in eyes open and eyes closed conditions for 5 minutes each, with a 19-channel wireless EEG device. The VR intervention program (3 times/week, 100 min each session) comprised four types of VR game-based content to improve the attention, memory and processing speed. Analysis of the subjects for group-time interactions revealed that the intervention group exhibited a significantly improved executive function and brain function at the resting state. Additionally, gait speed and mobility were also significantly improved between and after the follow-up. The VR-based training program improved cognitive and physical function in patients with MCI relative to controls. Encouraging patients to perform VR and game-based training may be beneficial to prevent cognitive decline.

Indexed as

dementiaelectroencephalogrammild cognitive impairmentvirtual reality

Identifiers

PMID32365533
PMCPMC7288029
OpenAlexW3022159292

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.