ArticleCells2020
A Functional Binding Domain in the Rbpr2 Receptor Is Required for Vitamin A Transport, Ocular Retinoid Homeostasis, and Photoreceptor Cell Survival in Zebrafish.
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In one paragraph
Article in Cells, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 20 citations in OpenAlex.
- Loss of the vitamin A receptor RBPR2 in mice disrupts whole-body retinoid homeostasis and the quantitative balance regulating retinylidene protein synthesis.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025Article
- The Absorption, Storage, and Transport of Ocular Carotenoids and Retinoids.Annual review of vision science · 2024Review
- The Logistical Backbone of Photoreceptor Cell Function: Complementary Mechanisms of Dietary Vitamin A Receptors and Rhodopsin Transporters.International journal of molecular sciences · 2024Review
- Vitamin A Deficiency Screening in Patients With Chronic Alcohol-Associated Liver Disease: Implications for Liver Transplant Candidates.ACG case reports journal · 2023Article
- Mapping of the extracellular RBP4 ligand binding domain on the RBPR2 receptor for Vitamin A transport.Frontiers in cell and developmental biology · 2023Article
- Mice Lacking the Systemic Vitamin A Receptor RBPR2 Show Decreased Ocular Retinoids and Loss of Visual Function.Nutrients · 2022Article
- Genetic dissection in mice reveals a dynamic crosstalk between the delivery pathways of vitamin A.Journal of lipid research · 2022Article
- Retinoid Homeostasis and Beyond: How Retinol Binding Protein 4 Contributes to Health and Disease.Nutrients · 2022Review
- Vitamin A Transporters in Visual Function: A Mini Review on Membrane Receptors for Dietary Vitamin A Uptake, Storage, and Transport to the Eye.Nutrients · 2021Review
- Loss of Motor Protein MYO1C Causes Rhodopsin Mislocalization and Results in Impaired Visual Function.Cells · 2021Article
- Biological Functions of RBP4 and Its Relevance for Human Diseases.Frontiers in physiology · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 3 institutions in 2 countries.
Ashish K SolankiDepartment of Medicine, Medical University of South Carolina, Charleston, SC 29425, USA.ORCID 0000-0002-5043-1699
Altaf A KondkarGlaucoma Research Chair, Department of Ophthalmology, College of Medicine, King Saud University, Riyadh 11411, Saudi Arabia.
Joseph FogertyDepartment of Ophthalmic Research, Cole Eye Institute, Cleveland Clinic, Cleveland, OH 44195, USA.
Yanhui SuDepartment of Medicine, Medical University of South Carolina, Charleston, SC 29425, USA.
Seok-Hyung KimDepartment of Medicine, Medical University of South Carolina, Charleston, SC 29425, USA.
Joshua H LipschutzDepartment of Medicine, Medical University of South Carolina, Charleston, SC 29425, USA.
Deepak NihalaniDepartment of Medicine, Medical University of South Carolina, Charleston, SC 29425, USA.
Brian D PerkinsDepartment of Ophthalmic Research, Cole Eye Institute, Cleveland Clinic, Cleveland, OH 44195, USA.
Glenn P LoboDepartment of Medicine, Medical University of South Carolina, Charleston, SC 29425, USA.
Medical University of South Carolina · USCleveland Clinic · USKing Saud University · SA
Funding
South Carolina Clinical & Translational Research Institute (SCTR)UL1TR001450 · NCATS · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI BRADY, KATHLEEN T., FLUME, PATRICK A · 2015 to 2024
$41.1MUAB Recessive PKD Research and Translational Core CenterP30DK074038 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI YODER, BRADLEY K. · 2005 to 2019
$16.6MProteomics CoreP30DK123704 · NIDDK · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI DON C. ROCKEY · 2020 to 2026
$8.8MRESOURCE/SERVICE CORE C - MOLECULAR INFORMATICS MODULEP30EY025585 · NEI · CLEVELAND CLINIC LERNER COM-CWRU · PI BELA ANAND-APTE · 2016 to 2026
$7.7MMyo1c Participates in Podocyte Junction Formation Through Interaction with Neph1R01DK087956 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI NIHALANI, DEEPAK · 2010 to 2018
$3.5MPhysiological Role of the Vitamin A Transporter RBPR2 for VisionR01EY030889 · NEI · UNIVERSITY OF MINNESOTA · PI LOBO, GLENN P · 2020 to 2024
$1.8MStimulating Retina Regeneration from Muller Cells in Progressive Retinal DegenerationsR01EY030574 · NEI · CLEVELAND CLINIC LERNER COM-CWRU · PI PERKINS, BRIAN D · 2020 to 2022
$1.6MPhysiological Role of the Zebrafish Retinol Receptor rbpr2 in VisionR21EY025034 · NEI · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI LOBO, GLENN P · 2015 to 2016
$436kClinical Assessment of a novel non-invasive assay for diagnosing recurrent focal and segmental glomerulosclerosisR03TR003038 · NCATS · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI ARIF, EHTESHAM · 2019 to 2020
$150kPreclinical therapeutic validation of a novel therapeutic lead for treating glomerular diseases such as focal and segmental glomerulosclerosisR56DK116887 · NIDDK · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI NIHALANI, DEEPAK, SCHNELLMANN, RICK G · 2018 to 2018
$100kNCATS NIH HHS R03 TR003038NCATS NIH HHS UL1 TR001450NEI NIH HHS P30 EY025585NEI NIH HHS R01 EY030574NEI NIH HHS R01 EY030889NEI NIH HHS R21 EY025034NIDDK NIH HHS P30 DK074038NIDDK NIH HHS P30 DK123704NIDDK NIH HHS R01 DK087956NIDDK NIH HHS R56 DK116887
Abstract
Dietary vitamin A/all-
Indexed as
AnimalsCarrier ProteinsCell SurvivalEyeHomeostasisLiverMembrane ProteinsPhotoreceptor CellsRetinoidsVitamin AZebrafishZebrafish ProteinsCarrier ProteinsMembrane ProteinsRetinoidsVitamin AZebrafish Proteinsall-trans retinol transportphotoreceptor cellRBP4Rbpr2retinoidsretinol binding protein 4 receptor 2STRA6visionzebrafish
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Read underepoch 390
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.