Evidence map›Paper›PMID 32365107›Full record

ArticlePloS one2020

Incidence of haematological malignancies in Kosovo-A post "uranium war" concern.

Hatixhe Latifi-Pupovci, Miranda Selmonaj, Blerina Ahmetaj-Shala, Mimoza Dushi, Violeta Grajqevci

Open access · goldAbstract readHistorical Article
In one paragraph

Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 8 citations in OpenAlex.

  1. Trends of incidence, mortality and survival of multiple myeloma in Spain. A twenty-three-year population-based study.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Hatixhe Latifi-PupovciDepartment of Physiology and Immunology, Faculty of Medicine, University of Prishtina, Prishtina, Kosovo.
Miranda SelmonajDepartment of Physiology and Immunology, Faculty of Medicine, University of Prishtina, Prishtina, Kosovo.
Blerina Ahmetaj-ShalaNational Heart and Lung Institute, Imperial College, London, United Kingdom.ORCID 0000-0003-4488-7689
Mimoza DushiDepartment of Geography, Faculty of Natural Sciences, University of Prishtina, Prishtina, Kosovo.
Violeta GrajqevciDepartment of Paediatrics, Faculty of Medicine, University of Prishtina, Prishtina, Kosovo.
University of Prishtina · XKImperial College London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDuring the Kosovo War (1998-99) approximately 31,000 rounds with Depleted Uranium (DU) were fired on 85 targets in Kosovo. The number of haematological malignancies (HM) increased after the war and the concern was the use of DU during the war. The aim of this study was to analyse the incidence rates of HM in Kosovo throughout a 20-year that includes pre- and post- war period (1995-2015); and to examine if there is any association between the use of DU rounds and incidence rates of HM in different regions of Kosovo.

methodsIn this retrospective register-based study, 1,798 new patients diagnosed with leukaemia, Hodgkin lymphoma, non-Hodgkin lymphoma and Multiple myeloma were analysed over a 20 year period. Incidence rates were calculated focusing on specific time periods, regions and age-groups. In addition, the correlation between the use of DU in different regions and their incidence of HM was analysed.

resultsThe average annual crude rate of all HM in Kosovo was 5.02 cases per 100,000 persons. Incidence rates of HM in first post-war period (2000-2003) increased by 0.37 cases/100,000 persons (9.51%) compared to the pre-war period (1995-1998) whereas in the last post-war period (2012-2015), incidence of HM increased by 3.19/100,000 persons (82%). Gjakova and Peja, the first and third most exposed regions to DU ordnance ranked first and second in difference in HM. Prishtina, Gjilan and Ferizaj, regions with the least number of rounds/km2, were characterized by a decline of incidence rates.

conclusionsAfter the war, the increase in incidence rate of HM was higher in two regions with most DU rounds/km2 expended Despite these findings, this study warrants further investigation and does not lead us to a conclusive finding on the existence of a causal relationship between the use of DU during the war and the rise in incidence of HM in Kosovo.

Indexed as

UraniumWarfareAdolescentAdultAgedAged, 80 and overChildChild, PreschoolFemaleHematologic NeoplasmsHistory, 20th CenturyHistory, 21st CenturyHumansIncidenceInfantInfant, NewbornUranium

Identifiers

PMID32365107
PMCPMC7197787
OpenAlexW3023546133

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.