Evidence map›Paper›PMID 32364950›Full record

ArticleJournal of the mechanical behavior of biomedical materials2020

Analysis of multiple shear wave modes in a nonlinear soft solid: Experiments and finite element simulations with a tilted acoustic radiation force.

Annette Caenen, Anna E Knight, Ned C Rouze, Nick B Bottenus, Patrick Segers, Kathryn R Nightingale

Abstract read
In one paragraph

Article in Journal of the mechanical behavior of biomedical materials, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. 3D rotational shear wave elasticity imaging (3D-RSWEI) in anisotropic lattice phantoms.Journal of the mechanical behavior of biomedical materials · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Annette CaenenIBiTech-bioMMeda, Ghent University, Ghent, Belgium; Department of Cardiology, University Medical Center Rotterdam, Erasmus MC, Rotterdam, The Netherlands. Electronic address: annette.caenen@ugent.be.
Anna E KnightDepartment of Biomedical Engineering, Duke University, Durham, NC, United States.
Ned C RouzeDepartment of Biomedical Engineering, Duke University, Durham, NC, United States.
Nick B BottenusDepartment of Biomedical Engineering, Duke University, Durham, NC, United States.
Patrick SegersIBiTech-bioMMeda, Ghent University, Ghent, Belgium.
Kathryn R NightingaleDepartment of Biomedical Engineering, Duke University, Durham, NC, United States.

Funding

Radiation Force Imaging of Prostate Cancer and Guidance of Biopsy ProceduresR01CA142824 · NCI · DUKE UNIVERSITY · PI NIGHTINGALE, KATHRYN RADABAUGH · 2010 to 2021
$4.4M
Training in Medical ImagingT32EB001040 · NIBIB · DUKE UNIVERSITY · PI NIGHTINGALE, KATHRYN RADABAUGH · 2003 to 2018
$4.4M
Improved ultrasound imaging using elevated acoustic outputR01EB022106 · NIBIB · DUKE UNIVERSITY · PI NIGHTINGALE, KATHRYN RADABAUGH · 2016 to 2019
$1.8M
NCI NIH HHS R01 CA142824NIBIB NIH HHS R01 EB022106NIBIB NIH HHS T32 EB001040
6 · The paper itself

Abstract

Tissue nonlinearity is conventionally measured in shear wave elastography by studying the change in wave speed caused by the tissue deformation, generally known as the acoustoelastic effect. However, these measurements have mainly focused on the excitation and detection of one specific shear mode, while it is theoretically known that the analysis of multiple wave modes offers more information about tissue material properties that can potentially be used to refine disease diagnosis. This work demonstrated proof of concept using experiments and finite element simulations in a uniaxially stretched phantom by tilting the acoustic radiation force excitation axis with respect to the material's symmetry axis. Using this unique set-up, we were able to visualize two propagating shear wave modes across the stretch direction for stretches larger than 140%. Complementary simulations were performed using material parameters determined from mechanical testing, which enabled us to convert the observed shear wave behavior into a correct representative constitutive law for the phantom material, i.e. the Isihara model. This demonstrates the potential of measuring shear wave propagation in combination with shear wave modeling in complex materials as a non-invasive alternative for mechanical testing.

Indexed as

Elasticity Imaging TechniquesAcousticsFinite Element AnalysisPhantoms, ImagingAcoustoelasticityConstitutive behaviorFinite element simulationsShear vertical/horizontal modeShear wave elastographyTissue nonlinearity

Identifiers

PMID32364950
PMCPMC7276634

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.