Evidence map›Paper›PMID 32364833›Full record

ArticleZebrafish2020

A Fast, Simple, and Affordable Technique to Measure Oxygen Consumption in Living Zebrafish Embryos.

Julie Somkhit, Roxane Loyant, Alexandre Brenet, Rahma Hassan-Abdi, Constantin Yanicostas, Mathieu Porceddu, Annie Borgne-Sanchez, Nadia Soussi-Yanicostas

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Zebrafish, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Julie SomkhitNeuroDiderot, Inserm U1141, Université de Paris, Paris, France.
Roxane LoyantMitologics SAS, Faculté de Médecine, Créteil, France.
Alexandre BrenetNeuroDiderot, Inserm U1141, Université de Paris, Paris, France.
Rahma Hassan-AbdiNeuroDiderot, Inserm U1141, Université de Paris, Paris, France.
Constantin YanicostasNeuroDiderot, Inserm U1141, Université de Paris, Paris, France.
Mathieu PorcedduMitologics SAS, Faculté de Médecine, Créteil, France.
Annie Borgne-SanchezMitologics SAS, Faculté de Médecine, Créteil, France.
Nadia Soussi-YanicostasNeuroDiderot, Inserm U1141, Université de Paris, Paris, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In all animal species, oxygen consumption is a key process that is partially impaired in a large number of pathological situations and thus provides informative details on the physiopathology of the disease. In this study, we describe a simple and affordable method to precisely measure oxygen consumption in living zebrafish larvae using a spectrofluorometer and the MitoXpress Xtra Oxygen Consumption Assay. In addition, we used zebrafish larvae treated with mitochondrial respiratory chain inhibitors, antimycin A or rotenone, to verify that our method enables precise and reliable measurements of oxygen consumption.

Indexed as

Oxygen ConsumptionAnimalsAntimycin AEmbryo, NonmammalianLarvaRotenoneZebrafishAntimycin ARotenoneoxygen consumptionrespirationzebrafish larvae

Identifiers

PMID32364833
PMCPMC7455472

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.