ArticleBiochemistry2020
ABHD12 and LPCAT3 Interplay Regulates a Lyso-phosphatidylserine-C20:4 Phosphatidylserine Lipid Network Implicated in Neurological Disease.
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Article in Biochemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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18citing papers in PubMed
2.2field-weighted citation impact, top 14% of its field
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 33 citations in OpenAlex.
- LPLAT11/MBOAT7-driven phosphatidylinositol remodeling ensures radial glial cell integrity in developing neocortex.iScience · 2026Article
- SnRNA-seq Interprets Mechanisms by which Three Glial Cell Types Influence Myelin Regeneration in Adult Drug-Resistant Epilepsy-Related Cognitive Impairment.Molecular neurobiology · 2025Article
- LC-MS-Based Untargeted Metabolic Profiling in Plasma Following Dapagliflozin Administration in Healthy Volunteers.Metabolites · 2025Article
- Impact of Psychological Stress and Spontaneous Tumour Regression on the Hippocampal Proteome in a Mouse Model of Breast Cancer.Journal of neurochemistry · 2025Article
- Case Report: novel GUCA1B and ABHD12 mutations in retinitis pigmentosa sine pigmento: expanding the genotypic spectrum through multimodal phenotyping.Frontiers in medicine · 2025Article
- PHARC syndrome: an overview.Orphanet journal of rare diseases · 2024Review
- From Classical to Alternative Pathways of 2-Arachidonoylglycerol Synthesis: AlterAGs at the Crossroad of Endocannabinoid and Lysophospholipid Signaling.Molecules (Basel, Switzerland) · 2024Review
- Integrative analysis of ferroptosis-related genes reveals that ABHD12 is a novel prognostic biomarker and facilitates hepatocellular carcinoma tumorigenesis.Discover oncology · 2024Article
- Lipid Quality Control and Ferroptosis: From Concept to Mechanism.Annual review of biochemistry · 2024Review
- Arachidonic Acid Mobilization and Peroxidation Promote Microglial Dysfunction in Aβ Pathology.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Regulatory Effects and Mechanisms of L-Theanine on Neurotransmitters via Liver-Brain Axis Under a High Protein Diet.Molecular neurobiology · 2024Article
- Increase in Cellular Lysophosphatidylserine Content Exacerbates Inflammatory Responses in LPS-Activated Microglia.Neurochemical research · 2022Article
- Research progress in the role and mechanism of LPCAT3 in metabolic related diseases and cancer.Journal of Cancer · 2022Review
- Current Knowledge on the Biology of Lysophosphatidylserine as an Emerging Bioactive Lipid.Cell biochemistry and biophysics · 2021Review
- The endocannabinoid system - current implications for drug development.Journal of internal medicine · 2021Review
- Remodeling glycerophospholipids affects obesity-related insulin signaling in skeletal muscle.The Journal of clinical investigation · 2021Article
- The Lysophosphatidylserines-An Emerging Class of Signalling Lysophospholipids.The Journal of membrane biology · 2020Review
- Mapping the Neuroanatomy of ABHD16A, ABHD12, and Lysophosphatidylserines Provides New Insights into the Pathophysiology of the Human Neurological Disorder PHARC.Biochemistry · 2020Article
Corrections and comments
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Authors and funding
14 authors at 3 institutions in 1 country.
Taka-Aki IchuDepartment of Chemistry, The Scripps Research Institute, La Jolla, California 92037, United States.
Alex ReedDepartment of Chemistry, The Scripps Research Institute, La Jolla, California 92037, United States.
Daisuke OgasawaraDepartment of Chemistry, The Scripps Research Institute, La Jolla, California 92037, United States.
Olesya UlanovskayaLundbeck, La Jolla, California 92121, United States.
Amanda RobertsDepartment of Molecular Medicine, The Scripps Research Institute, La Jolla, California 92037, United States.
Carlos A AguirreDepartment of Molecular Medicine, The Scripps Research Institute, La Jolla, California 92037, United States.
Liron Bar-PeledDepartment of Chemistry, The Scripps Research Institute, La Jolla, California 92037, United States.
Jie GaoPathology and Laboratory Medicine, University of California, Los Angeles, Los Angeles, California 90024, United States.
Jason GermainDepartment of Chemistry, The Scripps Research Institute, La Jolla, California 92037, United States.
Sabrina BarbasDepartment of Chemistry, The Scripps Research Institute, La Jolla, California 92037, United States.
Kim MasudaDepartment of Chemistry, The Scripps Research Institute, La Jolla, California 92037, United States.
Bruno ContiDepartment of Molecular Medicine, The Scripps Research Institute, La Jolla, California 92037, United States.
Peter TontonozPathology and Laboratory Medicine, University of California, Los Angeles, Los Angeles, California 90024, United States.
Benjamin F CravattDepartment of Chemistry, The Scripps Research Institute, La Jolla, California 92037, United States.ORCID 0000-0001-5330-3492
Scripps Research Institute · USUniversity of California, Los Angeles · USLundbeck (United States) · US
Funding
CHEMOPROTEOMIC METHODS FOR SERINE HYDROLASE INHIBITOR DEVELOPMENTR01DA033760 · NIDA · SCRIPPS RESEARCH INSTITUTE, THE · PI CRAVATT, BENJAMIN F, SCAMPAVIA, LOUIS DANIEL · 2012 to 2021
$5.1MLipid-Responsive E3 ubiquitin ligases in cholesterol metabolism and atheroscierosisR01HL136618 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI TONTONOZ, PETER J · 2018 to 2021
$2.4MThe Idol-ApoE receptor pathway in Alzheimer's diseaseR00AG054736 · NIA · OHIO STATE UNIVERSITY · PI GAO, JIE · 2019 to 2021
$747kIntegrated Acoustic Transfer System for HTS Library ManagementS10OD025279 · OD · SCRIPPS FLORIDA · PI SCAMPAVIA, LOUIS DANIEL · 2018 to 2018
$624kNHLBI NIH HHS R01 HL136618NIA NIH HHS R00 AG054736NIDA NIH HHS R01 DA033760NIH HHS S10 OD025279
Abstract
PHARC (polyneuropathy, hearing loss, cerebellar ataxia, retinitis pigmentosa, and cataract) is a human neurological disorder caused by deleterious mutations in the
Indexed as
1-Acylglycerophosphocholine O-AcyltransferaseAnimalsMiceMice, KnockoutMolecular StructureMonoacylglycerol LipasesNervous System DiseasesPhosphatidylserines1-Acylglycerophosphocholine O-AcyltransferaseAbhd12 protein, mouseLPCAT3 protein, mouseMonoacylglycerol LipasesPhosphatidylserines
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Read underepoch 390
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.