Evidence map›Paper›PMID 32364619›Full record

ArticleThe Laryngoscope2020

Nasal Airflow Changes With Bioabsorbable Implant, Butterfly, and Spreader Grafts.

Bryan M Brandon, Wesley H Stepp, Saikat Basu, Julia S Kimbell, Brent A Senior, William W Shockley, J Madison Clark

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Laryngoscope, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
  2. Article
  3. Functional nasal surgery in the office-based setting.World journal of otorhinolaryngology - head and neck surgery · 2023
    Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Bryan M BrandonDepartment of Otolaryngology, University of North Carolina, School of Medicine, Chapel Hill, North Carolina, U.S.A.
Wesley H SteppDepartment of Otolaryngology, University of North Carolina, School of Medicine, Chapel Hill, North Carolina, U.S.A.ORCID 0000-0003-2213-1872
Saikat BasuDepartment of Otolaryngology, University of North Carolina, School of Medicine, Chapel Hill, North Carolina, U.S.A.ORCID 0000-0003-1464-8425
Julia S KimbellDepartment of Otolaryngology, University of North Carolina, School of Medicine, Chapel Hill, North Carolina, U.S.A.ORCID 0000-0002-1969-6373
Brent A SeniorDepartment of Otolaryngology, University of North Carolina, School of Medicine, Chapel Hill, North Carolina, U.S.A.
William W ShockleyDepartment of Otolaryngology, University of North Carolina, School of Medicine, Chapel Hill, North Carolina, U.S.A.
J Madison ClarkDepartment of Otolaryngology, University of North Carolina, School of Medicine, Chapel Hill, North Carolina, U.S.A.
University of North Carolina at Chapel Hill · US

Funding

MEDICAL SCIENTIST TRAINING PROGRAMT32GM008719 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DARVILLE, TONI, DESHMUKH, MOHANISH P · 1999 to 2023
$15.1M
Improving Topical Drug Delivery for Treatment of Chronic RhinosinusitisR01HL122154 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI KIMBELL, JULIA SPENCER · 2015 to 2018
$1.5M
NHLBI NIH HHS R01 HL122154NIGMS NIH HHS T32 GM008719
6 · The paper itself

Abstract

objectives/hypothesisInternal nasal valve compromise is a major cause of nasal obstruction, with a growing number of ways to treat this condition. In this study, we compared the effects of butterfly graft, spreader graft, and the bioabsorbable nasal implant on nasal airflow resistance. STUDY

designCadaver study.

methodsComputational fluid dynamics (CFD) simulations were completed from nine preoperative and postoperative cadaveric subjects. Each cadaveric head underwent placement of a bioabsorbable nasal implant (BNI) (Spirox Latera; Stryker ENT, Plymouth, MN), butterfly graft, or spreader graft. Pre- and postoperative computed tomography (CT) scans were used to generate three-dimensional models of the nasal airway used in steady-state CFD simulations of airflow and heat transfer during inspiration.

resultsButterfly graft placement resulted in a mean improvement in nasal airway resistance of 24.9% (±7.3), whereas BNI placement resulted in a 6.7% (±1.2) improvement, and spreader graft placement also resulted in a consistent improvement of 2.6% (±13.5). Pressure within the main nasal cavity was consistently lower following butterfly graft placement versus a spreader graft or BNI. Butterfly and spreader graft placement also resulted in modest improvements in airflow allocation, whereas BNI demonstrated more variation (-1% to 12%). Heat flux was not significantly different; however, a small improvement in total heat flux was seen with all three interventions.

conclusionsThe results of this study demonstrate reduction in nasal airway resistance in all three surgical interventions, with the butterfly graft demonstrating superiority to the other two techniques. However, these data only reflect a static environment and not dynamic changes in airflow seen during respiration. LEVEL OF EVIDENCE: NA Laryngoscope, 130:E817-E823, 2020.

Indexed as

Absorbable ImplantsAirway ResistanceCadaverEar CartilageHumansHydrodynamicsNasal CartilagesNasal ObstructionPatient-Specific ModelingRhinoplastySuture TechniquesTomography, X-Ray Computedbioabsorbable nasal implantbutterfly graftinternal nasal valve repairNasal valve collapsespreader graft

Identifiers

PMID32364619
PMCPMC7609515
OpenAlexW3022142567

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.