Evidence map›Paper›PMID 32364424›Full record

ArticleCancer biology & therapy2020

Copy number variation of ubiquitin- specific proteases genes in blood leukocytes and colorectal cancer.

Tian Tian, Haoran Bi, Yupeng Liu, Guangxiao Li, Yiwei Zhang, Liming Cao, Fulan Hu, Yashuang Zhao, Huiping Yuan

Open access · bronzeAbstract read
In one paragraph

Article in Cancer biology & therapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Adap-BDCM: Adaptive Bilinear Dynamic Cascade Model for Classification Tasks on CNV Datasets.Interdisciplinary sciences, computational life sciences · 2024
    Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Tian TianDepartment of Epidemiology, Public Health College of Harbin Medical University , Harbin, P.R. China.
Haoran BiDepartment of Epidemiology, Public Health College of Harbin Medical University , Harbin, P.R. China.
Yupeng LiuDepartment of Epidemiology, Public Health College of Harbin Medical University , Harbin, P.R. China.
Guangxiao LiDepartment of Epidemiology, Public Health College of Harbin Medical University , Harbin, P.R. China.
Yiwei ZhangDepartment of Epidemiology, Public Health College of Harbin Medical University , Harbin, P.R. China.
Liming CaoDepartment of Epidemiology, Public Health College of Harbin Medical University , Harbin, P.R. China.
Fulan HuDepartment of Epidemiology, Public Health College of Harbin Medical University , Harbin, P.R. China.
Yashuang ZhaoDepartment of Epidemiology, Public Health College of Harbin Medical University , Harbin, P.R. China.
Huiping YuanDepartment of Ophthalmology, The Second Affiliated Hospital of Harbin Medical University , Harbin, P.R. China.
Harbin Medical University · CNSecond Affiliated Hospital of Harbin Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ubiquitin-specific proteases (USPs) play important roles in the regulation of many cancer-related biological processes. USPs copy number variation (CNVs) may affect the risk and prognosis of colorectal cancer (CRC). We detected CNVs of USPs genes in 468 matched CRC patients and controls, estimated the associations between the USPs genes CNVs and CRC risk and prognosis and their interactions with environmental factors on CRC risk. Finally, we generated five CRC risk predictive models with different CNVs patterns combining with environmental factors (EF). We identified significant association between CYLD deletion and CRC risk (OR

Indexed as

Case-Control StudiesColorectal NeoplasmsDNA Copy Number VariationsFemaleHumansLeukocytesMaleMiddle AgedUbiquitin-Specific ProteasesUbiquitin-Specific ProteasesColorectal cancercopy number variationCYLDUSP11USP9X

Identifiers

PMID32364424
PMCPMC7515516
OpenAlexW3023722636

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.