Evidence map›Paper›PMID 32364214›Full record

ArticleChemical communications (Cambridge, England)2020

Nanogel receptors for high isoelectric point protein detection: influence of electrostatic and covalent polymer-protein interactions.

Marissa E Wechsler, H K H Jocelyn Dang, Samuel D Dahlhauser, Susana P Simmonds, James F Reuther, Jordyn M Wyse, Abigail N VandeWalle, Eric V Anslyn, Nicholas A Peppas

Abstract read
In one paragraph

Article in Chemical communications (Cambridge, England), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Charged Poly(ACS biomaterials science & engineering · 2021
    Article
  6. New Aldehyde-Functional Methacrylic Water-Soluble Polymers.Angewandte Chemie (International ed. in English) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Marissa E WechslerInstitute for Biomaterials, Drug Delivery, and Regenerative Medicine, The University of Texas at Austin, Austin, TX, USA.
H K H Jocelyn Dang
Samuel D Dahlhauser
Susana P Simmonds
James F Reuther
Jordyn M Wyse
Abigail N VandeWalle
Eric V Anslyn
Nicholas A Peppas

Funding

Sensor arrays based on molecularly imprinted polymers for diagnosis of Sjogren's syndromeR01EB022025 · NIBIB · UNIVERSITY OF TEXAS AT AUSTIN · PI ANSLYN, ERIC V., PEPPAS, NICHOLAS A · 2016 to 2019
$1.5M
NIBIB NIH HHS R01 EB022025
6 · The paper itself

Abstract

An aldehyde acrylate-based functional monomer was incorporated into poly(N-isopropylacrylamide-co-methacrylic acid) nanogels for use as protein receptors. The aldehyde component forms dynamic imines with surface exposed lysine residues, while carboxylic acid/carboxylate moieties form electrostatic interactions with high isoelectric point proteins. Together, these interactions effect protein adsorption and recognition.

Indexed as

AcrylamidesAdsorptionAlbuminsImmunoglobulin GIsoelectric PointLactoferrinLactoglobulinsMuramidaseNanogelsPolymethacrylic AcidsStatic ElectricityAcrylamidesAlbuminsImmunoglobulin GLactoferrinLactoglobulinsMuramidaseNanogelsPolymethacrylic Acidspoly(N-isopropylacrylamide-co-methacrylic acid)

Identifiers

PMID32364214
PMCPMC7377432

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.