ArticleTechnology and health care : official journal of the European Society for Engineering and Medicine2020
The effect of external voltage stimulation on absence seizures.
Article in Technology and health care : official journal of the European Society for Engineering and Medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed, 3 citations in OpenAlex.
- The inhibition mechanism of epilepsy disease in a computational model.Technology and health care : official journal of the European Society for Engineering and Medicine · 2022Article
- The therapeutic mechanism of epilepsy seizures in different target areas: Research on a theoretical model.Technology and health care : official journal of the European Society for Engineering and Medicine · 2021Article
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3 authors at 2 institutions in 1 country.
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Abstract
backgroundAbsence epilepsy (AE) is a systemic disease of the brain, which mainly occurs during childhood and adolescence. The control mechanism is still unclear, and few theoretical studies have been conducted to investigate this.
objectiveIn this paper, we employed external direct voltage stimulation in the subthalamic nucleus to explore mechanisms that inhibit absence seizures.
methodsAll simulation results are obtained by the four-order Runge-Kutta method in the MATLAB environment. The inhibition mechanism can be inferred from the results.
resultsWe found that the seizures may be inhibited by tuning the strength of the voltage to suitable ranges. This regulation may be achieved through the competition between the inhibitory projections from the basal ganglia to the thalamus.
conclusionBecause the mechanism underlying the treatment of epilepsy with a uniform direct current electric field is unclear, we hope that these results can inspire further experimental studies.
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