Evidence map›Paper›PMID 32364015›Full record

ArticleTissue engineering. Part C, Methods2020

Horseradish Peroxidase-Catalyzed Crosslinking of Fibrin Microthread Scaffolds.

Meagan E Carnes, Cailin R Gonyea, Rebecca G Mooney, Jane W Njihia, Jeannine M Coburn, George D Pins

Open access · bronzeAbstract read
In one paragraph

Article in Tissue engineering. Part C, Methods, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.7field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Meagan E CarnesDepartment of Biomedical Engineering, Worcester Polytechnic Institute, Worcester, Massachusetts, USA.
Cailin R GonyeaDepartment of Biomedical Engineering, Worcester Polytechnic Institute, Worcester, Massachusetts, USA.
Rebecca G MooneyDepartment of Biomedical Engineering, Bucknell University, Lewisburg, Pennsylvania, USA.
Jane W NjihiaDepartment of Chemical and Biomolecular Engineering, University of Maryland, College Park, Maryland, USA.
Jeannine M CoburnDepartment of Biomedical Engineering, Worcester Polytechnic Institute, Worcester, Massachusetts, USA.
George D PinsDepartment of Biomedical Engineering, Worcester Polytechnic Institute, Worcester, Massachusetts, USA.
Worcester Polytechnic Institute · USBucknell University · USUniversity of Maryland, College Park · US

Funding

Development of a Composite Cardiac Patch with Synchronized ContractilityR15HL137145 · NHLBI · WORCESTER POLYTECHNIC INSTITUTE · PI PINS, GEORGE D. · 2017 to 2017
$452k
NHLBI NIH HHS R15 HL137145
6 · The paper itself

Abstract

Horseradish peroxidase (HRP) has been investigated as a catalyst to crosslink tissue-engineered hydrogels because of its mild reaction conditions and ability to modulate the mechanical properties of the matrix. Here, we report the results of the first study investigating the use of HRP to crosslink fibrin scaffolds. We examined the effect of varying HRP and hydrogen peroxide (H

Indexed as

AnimalsBiocompatible MaterialsCross-Linking ReagentsFibrinHorseradish PeroxidaseHumansHydrogelsHydrogen PeroxideMaterials TestingTensile StrengthTissue EngineeringTissue ScaffoldsBiocompatible MaterialsCross-Linking ReagentsFibrinHorseradish PeroxidaseHydrogelsHydrogen Peroxidebiomaterialscrosslinkingdityrosineenzymatic crosslinkingfibrin microthreadshorseradish peroxidase

Identifiers

PMID32364015
PMCPMC7310227
OpenAlexW3021086748

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.