ArticleJournal of applied clinical medical physics2020
On the complexity of helical tomotherapy treatment plans.
Article in Journal of applied clinical medical physics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 13 citations in OpenAlex.
- Pancreatic SBRT on four modern platforms: dosimetric and radiobiological gains with the Ethos ring-gantry linac versus TrueBeam, Halcyon, and helical tomotherapy.Radiation oncology (London, England) · 2026Article
- Gantry-period-guided modulation factor selection in helical tomotherapy: effects on delivery efficiency, dosimetry and verification accuracy.Frontiers in oncology · 2026Article
- Predicting patient-specific quality assurance outcomes in helical tomotherapy using plan complexity and 3D dose-distribution radiomics.Frontiers in oncology · 2026Article
- A case study on optimizing helical tomotherapy parameters for small cell lung cancer with extensive pleural metastasis.Scientific reports · 2025Article
- Evaluation of dose delivery accuracy of the lung with the respiratory technique of the Radixact Synchrony real-time tumor tracking system.Technical innovations & patient support in radiation oncology · 2025Article
- Impact of delivery time factor on treatment time and plan quality in tomotherapy.Scientific reports · 2023Article
- Prediction models as decision-support tools for virtual patient-specific quality assurance of helical tomotherapy plans.Physics and imaging in radiation oncology · 2023Article
- Quantitative assessment of helical tomotherapy plans complexity.Journal of applied clinical medical physics · 2023Article
- Analysis of clinical patient-specific pre-treatment quality assurance with the new helical tomotherapy platform, following the AAPM TG-218 report.Radiation oncology (London, England) · 2021Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
purposeMultiple metrics are proposed to characterize and compare the complexity of helical tomotherapy (HT) plans created for different treatment sites.
methodsA cohort composed of 208 HT plans from head and neck (105), prostate (51) and brain (52) tumor sites was considered. For each plan, 14 complexity metrics were calculated. Those metrics evaluate the percentage of leaves with small opening times or approaching the projection duration, the percentage of closed leaves, the amount of tongue-and-groove effect, and the overall modulation of the planned sinogram. To enable data visualization, an approach based on principal component analysis was followed to reduce the dataset dimensionality. This allowed the calculation of a global plan complexity score. The correlation between plan complexity and pretreatment verification results using the Spearman's rank correlation coefficients was investigated.
resultsAccording to the global score, the most complex plans were the head and neck tumor cases, followed by the prostate and brain lesions irradiated with stereotactic technique. For almost all individual metrics, head and neck plans confirmed to be the plans with the highest complexity. Nevertheless, prostate cases had the highest percentage of leaves with an opening time approaching the projection duration, whereas the stereotactic brain plans had the highest percentage of closed leaves per projection. Significant correlations between some of the metrics and the pretreatment verification results were identified for the stereotactic brain group.
conclusionsThe proposed metrics and the global score demonstrated to be useful to characterize and quantify the complexity of HT plans of different treatment sites. The reported differences inter- and intra-group may be valuable to guide the planning process aiming at reducing uncertainties and harmonize planning strategies.
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