Evidence map›Paper›PMID 32363488›Full record

ArticleEuropean radiology experimental2020

Matteo Pardini, Flavio Nobili, Dario Arnaldi, Silvia Morbelli, Matteo Bauckneht, Roberto Rissotto, Carlo Serrati, Gianluca Serafini, Caterina Lapucci, Lucio Ghio and 7 more

Open access · goldAbstract readValidation Study
PubMed Full text at PMC Publisher
In one paragraph

Article in European radiology experimental, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 3 institutions in 1 country.

Matteo PardiniDepartment of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DINOGMI), University of Genoa, Genoa, Italy.
Flavio NobiliDepartment of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DINOGMI), University of Genoa, Genoa, Italy.
Dario ArnaldiDepartment of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DINOGMI), University of Genoa, Genoa, Italy.
Silvia MorbelliDepartment of Health Sciences (DISSAL), University of Genoa, Genoa, Italy.
Matteo BaucknehtDepartment of Health Sciences (DISSAL), University of Genoa, Genoa, Italy.
Roberto RissottoOspedale Policlinico San Martino IRCCS, Genoa, Italy.
Carlo SerratiOspedale Policlinico San Martino IRCCS, Genoa, Italy.
Gianluca SerafiniDepartment of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DINOGMI), University of Genoa, Genoa, Italy.
Caterina LapucciDepartment of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DINOGMI), University of Genoa, Genoa, Italy.
Lucio GhioPsychiatry Branch, Galliera Hospital, Genoa, Italy.
Mario AmoreDepartment of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DINOGMI), University of Genoa, Genoa, Italy.
Davide MassuccoNeurology Unit, Ospedale Antero Micone, Genoa, Italy.
Davide SassosOspedale Policlinico San Martino IRCCS, Genoa, Italy.
Laura BonzanoDepartment of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DINOGMI), University of Genoa, Genoa, Italy.
Giovanni Luigi MancardiDepartment of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DINOGMI), University of Genoa, Genoa, Italy.
Luca RoccatagliataDepartment of Health Sciences (DISSAL), University of Genoa, Genoa, Italy. lroccatagliata@neurologia.unige.it.
Disease Management Team on Dementia of the IRCCS Ospedale Policlinico San Martino, Genoa
University of Genoa · ITOspedale Policlinico San Martino · ITEnte Ospedaliero Ospedali Galliera · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAssessment of nigrostriatal degeneration is a key element to discriminate between dementia with Lewy bodies (DLB) and Alzheimer disease (AD), and it is often evaluated using ioflupane (

methodsA nigroputaminal bundle mask was delineated on 12 healthy volunteers (HV) and applied to MRI diffusion-weighted data of 18 subjects with DLB, 21 subjects with AD and another group of 12 HV. The correlation between nigroputaminal fractional anisotropy (FA) values and

resultsDLB patients showed a higher nigroputaminal FA values compared with both AD and HV-controls groups (p = 0.001 for both comparisons), while no difference was observed between HV-controls and AD groups (p = 0.450); at ROC analysis, the area under the curve for the discriminating DLB and AD subjects was 0.820; FA values correlated with

conclusionsIn DLB, nigroputaminal degeneration could be reliably assessed on MRI diffusion scans using a mask of nigroputaminal bundle trajectory. Nigroputaminal FA in DLB patients correlated with

Indexed as

AgedDiagnosis, DifferentialDiffusion Tensor ImagingFemaleHumansIodine RadioisotopesLewy Body DiseaseMalePutamenSubstantia NigraTomography, Emission-Computed, Single-PhotonTropanes2-carbomethoxy-8-(3-fluoropropyl)-3-(4-iodophenyl)tropaneIodine-123Iodine RadioisotopesTropanesAlzheimer diseaseDiffusion tensor imagingIoflupaneMagnetic resonance imagingsingle-photon)Tomography (emission-computed

Identifiers

PMID32363488
PMCPMC7196565
OpenAlexW3022408463

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.