Evidence map›Paper›PMID 32363482›Full record

Observational studyNeuroradiology2020

MRI follow-up after magnetic resonance-guided focused ultrasound for non-invasive thalamotomy: the neuroradiologist's perspective.

Vera C Keil, Valeri Borger, Veronika Purrer, Simon F Groetz, Lukas Scheef, Henning Boecker, Hans H Schild, Christine Kindler, Angelika Schmitt, Laszlo Solymosi and 2 more

Open access · hybridAbstract readObservational Study
In one paragraph

Observational study in Neuroradiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.9field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
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  3. Review
  4. Functional network reorganization following VIM-MRgFUS for essential tremor.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Vera C KeilDepartment of Neuroradiology, University Hospital Bonn, Venusberg-Campus 1, 53127, Bonn, Germany. vera.keil@ukbonn.de.ORCID https://orcid.org/0000-0001-8699-3506
Valeri BorgerDepartment of Neurosurgery, University Hospital Bonn, Venusberg-Campus 1, 53127, Bonn, Germany.
Veronika PurrerDepartment of Neurology, University Hospital Bonn, Venusberg-Campus 1, 53127, Bonn, Germany.
Simon F GroetzDepartment of Neuroradiology, University Hospital Bonn, Venusberg-Campus 1, 53127, Bonn, Germany.
Lukas ScheefDepartment of Radiology, University Hospital Bonn, Venusberg-Campus 1, 53127, Bonn, Germany.
Henning BoeckerDepartment of Radiology, University Hospital Bonn, Venusberg-Campus 1, 53127, Bonn, Germany.
Hans H SchildDepartment of Radiology, University Hospital Bonn, Venusberg-Campus 1, 53127, Bonn, Germany.
Christine KindlerDepartment of Neurology, University Hospital Bonn, Venusberg-Campus 1, 53127, Bonn, Germany.
Angelika SchmittDepartment of Radiology, University Hospital Bonn, Venusberg-Campus 1, 53127, Bonn, Germany.
Laszlo SolymosiDepartment of Neuroradiology, University Hospital Bonn, Venusberg-Campus 1, 53127, Bonn, Germany.
Ullrich WüllnerDepartment of Neurology, University Hospital Bonn, Venusberg-Campus 1, 53127, Bonn, Germany.
Claus C PieperDepartment of Radiology, University Hospital Bonn, Venusberg-Campus 1, 53127, Bonn, Germany.
University Hospital Bonn · DE

Funding

Deutsche Forschungsgemeinschaft 328023777
6 · The paper itself

Abstract

purposeMagnetic resonance-guided focused ultrasound (MRgFUS) systems are increasingly used to non-invasively treat tremor; consensus on imaging follow-up is poor in these patients. This study aims to elucidate how MRgFUS lesions evolve for a radiological readership with regard to clinical outcome.

methodsMRgFUS-induced lesions and oedema were retrospectively evaluated based on DWI, SWI, T2-weighted and T1-weighted 3-T MRI data acquired 30 min and 3, 30 and 180 days after MRgFUS (n = 9 essential tremor, n = 1 Parkinson's patients). Lesions were assessed volumetrically, visually and by ADC measurements and compared with clinical effects using non-parametric testing.

resultsThirty minutes after treatment, all lesions could be identified on T2-weighted images. Immediate oedema was rare (n = 1). Lesion volume as well as oedema reached a maximum on day 3 with a mean lesion size of 0.4 ± 0.2 cm

conclusionIn conclusion, cerebral MRgFUS lesions variably shrink over months. SWI is the sequence of choice to identify lesions after 6 months. Lesion volume is arguably associated with intermediate-term outcome.

Indexed as

Magnetic Resonance Imaging, InterventionalUltrasonic TherapyAgedEssential TremorFemaleFollow-Up StudiesHumansMaleParkinson DiseaseRetrospective StudiesThalamusEssential tremorHigh-intensity focused ultrasound ablationMagnetic resonance imagingParkinson disease

Identifiers

PMID32363482
PMCPMC7410861
OpenAlexW3023583419

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.