ArticleInternational journal of colorectal disease2020
Impacts of anemia and transfusion on oncologic outcomes in patients undergoing surgery for colorectal cancer.
Article in International journal of colorectal disease, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.
- Plasma 25-hydroxyvitamin D deficiency in the peri-operative period is associated with survival outcome in colorectal cancer patients: a meta-analysis.BMC surgery · 2024Pooled it
- Impact of Preoperative Anemia on Short-Term Outcomes After Colorectal Cancer Surgery: How the Choice of Diagnostic Criteria Leads to Conflicting Findings.Clinical Medicine Insights. Oncology · 2026Article
- Impact of preoperative anemia on short- and long-term outcomes of sphincter-preserving rectal cancer surgery.Discover oncology · 2025Article
- Predictive value of red blood cell distribution width and hematocrit for short-term outcomes and prognosis in colorectal cancer patients undergoing radical surgery.World journal of gastroenterology · 2024Article
- Lower need for allogeneic blood transfusion after robotic low anterior resection compared with open low anterior resection: a propensity score-matched analysis.Journal of robotic surgery · 2023Article
- Prehabilitation for patients with colorectal cancer: a snapshot of current daily practice in Dutch hospitals.Perioperative medicine (London, England) · 2023Article
- Preoperative Identification and Management of Anemia in the Colorectal Surgery Patient.Clinics in colon and rectal surgery · 2023Review
- Preoperative anemia and long-term survival in patients undergoing colorectal cancer surgery: a retrospective cohort study.World journal of surgical oncology · 2023Article
- Risk Factors for Severe Postoperative Complications after Oncologic Right Colectomy: Unicenter Analysis.Medicina (Kaunas, Lithuania) · 2022Article
- Anemia tolerance versus blood transfusion on long-term outcomes after colorectal cancer surgery: A retrospective propensity-score-matched analysis.Frontiers in oncology · 2022Article
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
purposeThis study aimed to evaluate the prevalence of preoperative anemia and impacts of anemia and transfusion on survival in patients undergoing surgery for colorectal cancer.
methodsThis study included patients who underwent surgery for primary colorectal cancer between 2011 and 2012. The influence of preoperative anemia and postoperative transfusion on recurrence-free survival and overall survival were retrospectively investigated. Anemia was defined as hemoglobin level < 13 g/dL in males and < 12 g/dL in females. The primary outcome was the prevalence of preoperative anemia in patients with colorectal cancer. Secondary outcomes included preoperative anemia management, postoperative 30-day mortality and morbidity, tumor recurrence, and overall survival.
resultsAmong a total of 1899 patients, 823 patients (43.3%) were anemic preoperatively, and 264 patients (13.9%) received postoperative transfusions. Postoperative transfusion was associated with 30-day postoperative complications (OR = 1.514, 95% CI = 1.020 ~ 2.247) but not preoperative anemia (OR = 1.143, 95% CI, 0.811 ~ 1.611). Preoperative anemia (HR = 1.459, 95% CI = 1.104 ~ 1.929) and postoperative transfusion (HR = 1.566, 95% CI = 1.089 ~ 2.252) were significantly associated with worse recurrence-free survival in multivariable analysis. Preoperative anemia (HR = 1.572, 95% CI = 1.274 ~ 1.940) and postoperative transfusion (HR = 1.381, 95% CI = 1.076 ~ 1.773) were significant independent risk factors for worse overall survival.
conclusionsPreoperative anemia and postoperative transfusion were associated with worse survival in patients undergoing surgery for colorectal cancer. An alternative therapy to treat anemia and reduce transfusions should be introduced to improve oncologic outcomes.
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