SynthesisPsychopharmacology2020
Risky decision-making in individuals with substance use disorder: A meta-analysis and meta-regression review.
Synthesis in Psychopharmacology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
52 citing papers in PubMed, 87 citations in OpenAlex.
- Decision-Making Styles as a Moderator on the Efficacy of theSubstance use & misuse · 2023Trial
- Sex-specific effects of the atypical antipsychotic risperidone on performance in a risky decision-making task.Behavioural brain research · 2027Article
- Less systematic decision-making during delay discounting, but not discounting rate, is robustly linked to psychopathology.Journal of psychopathology and clinical science · 2026Article
- Substance use and the value of control.Cognitive, affective & behavioral neuroscience · 2026Article
- Chemogenetic inhibition of the anterior cingulate cortex increases safe decision-making in aged mice performing the Iowa Gambling Task.Psychopharmacology · 2026Article
- Histone deacetylase inhibitor sodium butyrate increases risk-taking during acquisition of the rat gambling task.Psychopharmacology · 2026Article
- Right‑DLPFC rTMS Transiently Modulates Risky Decision-Making and EEG Oscillatory Activity.Brain and behavior · 2026Article
- Sex-specific increased reactivity of the PVT and prolonged PVT→CeA circuit engagement following psilocin administration.Nature communications · 2026Article
- Chemogenetic modulation of the prelimbic cortex to the nucleus accumbens core pathway reduces cocaine-induced increase of risk preference.Translational psychiatry · 2026Article
- The role of ovarian hormones in risk aversion in female rats.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026Article
- Opioid misuse and sexually transmitted infections among U.S. college students: a cross-sectional analysis of the ACHA-NCHA III.BMC public health · 2026Article
- The relationship between regular substance use and cost comparisons in stable and volatile learning contexts.Translational psychiatry · 2026Article
- Abnormal Exploratory Tendencies in Risk Decision-Making in Gambling Disorder: Evidence from the Balloon Analogue Risk Task.Journal of gambling studies · 2025Article
- A novel cost-benefit decision-making task involving cued punishment: Effects of sex and psychostimulant administration.Behavioural brain research · 2025Article
- Largely Intact But Less Reliable and Distributed Neural Representations of Subjective Value in Human Opioid Addiction.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Effects of systemic oxytocin receptor activation and blockade on risky decision making in female and male rats.Behavioral neuroscience · 2025Article
- Who Engages in Simultaneous Gambling and Alcohol Use, and Why? A Mixed-Method Study.Journal of gambling studies · 2025Article
- Higher alcohol use is associated with subsequent increased risk seeking toward gains: A longitudinal cohort study in young men.Alcohol, clinical & experimental research · 2025Article
- Reduced Sensitivity to Negative Feedback May Lead to Risky Decision-Making in Amphetamine Users.Addiction biology · 2025Article
- Examining concordance between emotion-dependent risk-taking in the laboratory and in the real-world.Behaviour research and therapy · 2025Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundThis review aims to identify whether risky decision-making is increased in substance users, and the impact of substance type, polysubstance use status, abstinence period, and treatment status on risky decision-making.
methodsA literature search with no date restrictions was conducted to identify case-control studies or cross-sectional studies that used behavioral tasks to measure risky decision-making in substance users. A random-effects model was performed. GRADE criteria was used to assess the quality of evidence.
results52 studies were enrolled. The result showed that the difference in risky decision-making performance between user groups and control groups was significant (SMD = - 0.590; 95%CI = - 0.849 to - 0.330; p < 0.001; I
conclusionsThe results show that substance use is associated with impaired risky decision-making, indicating that interventions targeting risky decision-making in substance users should be developed for relapse prevention and rehabilitation.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.