Evidence map›Paper›PMID 32363421›Full record

ArticleEuropean journal of clinical pharmacology2020

Prescription analgesia and adjuvant use by pain severity at admission among nursing home residents with non-malignant pain.

Kate L Lapane, Anne L Hume, Reynolds A Morrison, Bill M Jesdale

Abstract read
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Article in European journal of clinical pharmacology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Kate L LapaneDepartment of Population and Quantitative Health Science, University of Massachusetts Medical School, 368 Plantation Street, Worcester, MA, 01605, USA. kate.lapane@umassmed.edu.
Anne L HumeDepartment of Family Medicine, Alpert Medical School, Brown University, Memorial Hospital of Rhode Island, Providence, RI, 02903, USA.
Reynolds A MorrisonDepartment of Population and Quantitative Health Science, University of Massachusetts Medical School, 368 Plantation Street, Worcester, MA, 01605, USA.
Bill M JesdaleDepartment of Population and Quantitative Health Science, University of Massachusetts Medical School, 368 Plantation Street, Worcester, MA, 01605, USA.

Funding

University of Massachusetts Center for Clinical and Translational ScienceTL1TR001454 · NCATS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI LEWIS, BRIAN C · 2015 to 2024
$3.6M
Non-malignant Pain in Nursing Home ResidentsR01NR016977 · NINR · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI LAPANE, KATE L · 2017 to 2021
$2.8M
NCATS NIH HHS TL1 TR001454NINR NIH HHS R01 NR016977NINR NIH HHS R01NR19677
6 · The paper itself

Abstract

objectiveWe estimated the use of prescribed analgesics and adjuvants among nursing home residents without cancer who reported pain at their admission assessment, in relation to resident-reported pain severity.

methodsMedicare Part D claims were used to define 3 classes of analgesics and 7 classes of potential adjuvants on the 21st day after nursing home admission (or the day of discharge for residents discharged before that date) among 180,780 residents with complete information admitted between January 1, 2011 and December 9, 2016, with no cancer diagnosis.

resultsOf these residents, 27.9% reported mild pain, 46.6% moderate pain, and 25.6% reported severe pain. The prevalence of residents in pain without Part D claims for prescribed analgesic and/or adjuvant medications was 47.3% among those reporting mild pain, 35.7% among those with moderate pain, and 24.8% among those in severe pain. Among residents reporting severe pain, 33% of those ≥ 85 years of age and 35% of those moderately cognitively impaired received no prescription analgesics/adjuvants. Use of all classes of prescribed analgesics and adjuvants increased with resident-reported pain severity, and the concomitant use of medications from multiple classes was common.

conclusionAmong nursing home residents with recognized pain, opportunities to improve the pharmacologic management of pain, especially among older residents, and those living with cognitive impairments exist.

Indexed as

Chemotherapy, AdjuvantAgedAged, 80 and overAnalgesiaAnalgesicsAnticonvulsantsAntidepressive AgentsFemalegamma-Aminobutyric AcidGlucocorticoidsHumansMaleMiddle AgedNeuromuscular AgentsNursing HomesPainAnalgesicsAnticonvulsantsAntidepressive Agentsgamma-Aminobutyric AcidGlucocorticoidsNeuromuscular AgentsAnalgesicsNursing homesPainPain severity

Identifiers

PMID32363421
PMCPMC7306024

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.