ArticleSocial cognitive and affective neuroscience2020
The social brain in female autism: a structural imaging study of twins.
Article in Social cognitive and affective neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 20 citations in OpenAlex.
- Theory of Mind in Myotonic Dystrophy Type 1 Is Associated With Cortical Gyrification and White Matter Hyperintensities.European journal of neurology · 2025Article
- Sex differences in trajectories of cortical development in autistic children from 2-13 years of age.Molecular psychiatry · 2024Article
- Sex modulation of faces prediction error in the autistic brain.Communications biology · 2024Article
- Investigating Sex-Based Neural Differences in Autism and Their Extended Reality Intervention Implications.Brain sciences · 2023Review
- EEG functional connectivity in infants at elevated familial likelihood for autism spectrum disorder.Molecular autism · 2023Article
- Reduced brain connectivity along the autism spectrum controlled for familial confounding by co-twin design.Scientific reports · 2023Article
- Sex-Related Changes in the Clinical, Genetic, Electrophysiological, Connectivity, and Molecular Presentations of ASD: A Comparison between Human and Animal Models of ASD with Reference to Our Data.International journal of molecular sciences · 2023Review
- Social visual preference mediates the effect of cortical thickness on symptom severity in children with autism spectrum disorder.Frontiers in psychiatry · 2023Article
- Altered Periodic Dynamics in the Default Mode Network in Autism and Attention-Deficit/Hyperactivity Disorder.Biological psychiatry · 2022Article
- The role of head circumference and cerebral volumes to phenotype male adults with autism spectrum disorder.Brain and behavior · 2022Article
- A co-twin-control study of altered sensory processing in autism.Autism : the international journal of research and practice · 2021Article
- Behavioral and biological divergence in monozygotic twin pairs discordant for autism phenotypes: A systematic review.JCPP advances · 2021Article
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Authors and funding
7 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A female advantage in social cognition (SoC) might contribute to women's underrepresentation in autism spectrum disorder (ASD). The latter could be underpinned by sex differences in social brain structure. This study investigated the relationship between structural social brain networks and SoC in females and males in relation to ASD and autistic traits in twins. We used a co-twin design in 77 twin pairs (39 female) aged 12.5 to 31.0 years. Twin pairs were discordant or concordant for ASD or autistic traits, discordant or concordant for other neurodevelopmental disorders or concordant for neurotypical development. They underwent structural magnetic resonance imaging and were assessed for SoC using the naturalistic Movie for the Assessment of Social Cognition. Autistic traits predicted reduced SoC capacities predominantly in male twins, despite a comparable extent of autistic traits in each sex, although the association between SoC and autistic traits did not differ significantly between the sexes. Consistently, within-pair associations between SoC and social brain structure revealed that lower SoC ability was associated with increased cortical thickness of several brain regions, particularly in males. Our findings confirm the notion that sex differences in SoC in association with ASD are underpinned by sex differences in brain structure.
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