Evidence map›Paper›PMID 32363321›Full record

ArticleHepatology communications2020

Multispectral Imaging Enables Characterization of Intrahepatic Macrophages in Patients With Chronic Liver Disease.

Omar A Saldarriaga, Benjamin Freiberg, Santhoshi Krishnan, Arvind Rao, Jared Burks, Adam L Booth, Bradley Dye, Netanya Utay, Monique Ferguson, Abdellah Akil and 3 more

Open access · goldAbstract read
In one paragraph

Article in Hepatology communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 33 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Integrating Molecular Testing With Clinical Criteria and Histopathology Improves Diagnostic Precision in Immune-Mediated Liver Diseases.Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc · 2025
    Article
  6. Review
  7. Article
  8. Digital pathology for nonalcoholic steatohepatitis assessment.Nature reviews. Gastroenterology & hepatology · 2024
    Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Impaired Dendritic Cell Homing in COVID-19.Frontiers in medicine · 2021
    Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Omar A SaldarriagaDepartment of Pathology University of Texas Medical Branch Galveston TX.
Benjamin FreibergVisiopharm Hoersholm Denmark.
Santhoshi KrishnanDepartment of Electrical and Computer Engineering Rice University Houston TX.
Arvind RaoDepartment of Electrical and Computer Engineering Rice University Houston TX.
Jared BurksDepartment of Leukemia University of Texas MD Anderson Cancer Center Houston TX.
Adam L BoothDepartment of Pathology University of Texas Medical Branch Galveston TX.ORCID https://orcid.org/0000-0002-1231-4117
Bradley DyeDepartment of Pathology University of Texas Medical Branch Galveston TX.
Netanya UtayDepartment of Internal Medicine University of Texas Health Science Center at Houston Houston TX.
Monique FergusonDepartment of Internal Medicine University of Texas Medical Branch Galveston TX.
Abdellah AkilDepartment of Microbiology and Immunology University of Texas Medical Branch Galveston TX.
Minkyung YiDepartment of Microbiology and Immunology University of Texas Medical Branch Galveston TX.
Laura BerettaDepartment of Molecular and Cellular Oncology University of Texas MD Anderson Cancer Center Houston TX.ORCID https://orcid.org/0000-0002-2054-684X
Heather L StevensonDepartment of Pathology University of Texas Medical Branch Galveston TX.ORCID https://orcid.org/0000-0002-0645-7621
The University of Texas Medical Branch at Galveston · USThe University of Texas MD Anderson Cancer Center · USUniversity of Michigan · USThe University of Texas Health Science Center at Houston · US

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Scott Kopetz · 1985 to 2026
$290.8M
UTMB Clinical and Translational Science AwardKL2TR001441 · NCATS · UNIVERSITY OF TEXAS MED BR GALVESTON · PI AMEREDES, BILL T · 2015 to 2024
$4.0M
NCATS NIH HHS KL2 TR001441NCI NIH HHS P30 CA016672
6 · The paper itself

Abstract

Intrahepatic macrophages influence the composition of the microenvironment, host immune response to liver injury, and development of fibrosis. Compared with stellate cells, the role of macrophages in the development of fibrosis remains unclear. Multispectral imaging allows detection of multiple markers

Identifiers

PMID32363321
PMCPMC7193134
OpenAlexW3009560542

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.