ArticlePathogens & immunity2020
Effectiveness of Ultraviolet-C Light and a High-Level Disinfection Cabinet for Decontamination of N95 Respirators.
Article in Pathogens & immunity, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers, 8 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
58 citing papers in PubMed, 8 syntheses or guidelines pooled it.
- Decontaminating N95/FFP2 masks for reuse during the COVID-19 epidemic: a systematic review.Antimicrobial resistance and infection control · 2021Pooled it
- Mask decontamination methods (model N95) for respiratory protection: a rapid review.Systematic reviews · 2021Pooled it
- The efficacy of ultraviolet light-emitting technology against coronaviruses: a systematic review.The Journal of hospital infection · 2021Pooled it
- Safety in the practice of decontaminating filtering facepiece respirators: A systematic review.American journal of infection control · 2021Pooled it
- The COVID-19 pandemic and N95 masks: reusability and decontamination methods.Antimicrobial resistance and infection control · 2021Pooled it
- Personal protective equipment for reducing the risk of COVID-19 infection among health care workers involved in emergency trauma surgery during the pandemic: An umbrella review.The journal of trauma and acute care surgery · 2021Pooled it
- Efficacy and safety of disinfectants for decontamination of N95 and SN95 filtering facepiece respirators: a systematic review.The Journal of hospital infection · 2020Pooled it
- Exploring options for reprocessing of N95 Filtering Facepiece Respirators (N95-FFRs) amidst COVID-19 pandemic: A systematic review.PloS one · 2020Pooled it
- Is UV-C light disinfection suitable as a disinfection method for medical devices: a scoping review.Antimicrobial resistance and infection control · 2025Article
- Practice of quality management for dental handpiece processing based on FOCUS-PDCA programme.BMC oral health · 2025Observational
- Evaluation of Far Ultraviolet-C Light for Decontamination of Organisms in Whole Milk and Chicken Manure.Pathogens & immunity · 2025Article
- Efficacy of an upper room ultraviolet-C (UV-C) technology versus far UV-C light technologies in reducing aerosolized bacteriophage MS2.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2025Article
- Microbiological evaluation of ultraviolet C light-emitting diodes for disinfection of medical instruments.Heliyon · 2024Article
- UV-C Light: A Promising Preservation Technology for Vegetable-Based Nonsolid Food Products.Foods (Basel, Switzerland) · 2023Review
- Design and Analysis of a Novel Ultraviolet-C Device for Surgical Face Mask Disinfection.ACS omega · 2022Article
- High altitude Relieves transmission risks of COVID-19 through meteorological and environmental factors: Evidence from China.Environmental research · 2022Article
- Effectiveness of germicidal ultraviolet light to inactivate coronaviruses on personal protective equipment to reduce nosocomial transmission.Infection control and hospital epidemiology · 2022Article
- Supercritical COThe Science of the total environment · 2022Article
- Clinical and experimental bacteriophage studies: Recommendations for possible approaches for standing against SARS-CoV-2.Microbial pathogenesis · 2022Review
- Is Peracetic Acid Fumigation Effective in Public Transportation?International journal of environmental research and public health · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundShortages of personal protective equipment (PPE) including N95 respirators are an urgent concern in the setting of the global COVID-19 pandemic. Decontamination of PPE could be useful to maintain adequate supplies, but there is uncertainty regarding the efficacy of decontamination technologies.
methodsA modification of the American Society for Testing and Materials standard quantitative carrier disk test method (ASTM E-2197-11) was used to examine the effectiveness of 3 methods, including ultraviolet-C (UV-C) light, a high-level disinfection cabinet that generates aerosolized peracetic acid and hydrogen peroxide, and dry heat at 70°C for 30 minutes. We assessed the decontamination of 3 commercial N95 respirators inoculated with methicillin-resistant
resultsUV-C administered as a 1-minute cycle in a UV-C box or a 30-minute cycle by a room decontamination device reduced contamination but did not meet criteria for decontamination of the viruses from all sites on the N95s. The high-level disinfection cabinet was effective for decontamination of the N95s and achieved disinfection with an extended 31-minute cycle. Dry heat at 70°C for 30 minutes was not effective for decontamination of the bacteriophages.
conclusionsUV-C could be useful to reduce contamination on N95 respirators. However, the UV-C technologies studied did not meet pre-established criteria for decontamination under the test conditions used. The high-level disinfection cabinet was more effective and met criteria for disinfection with an extended cycle.
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