Evidence map›Paper›PMID 32363186›Full record

ReviewFrontiers in bioengineering and biotechnology2020

Gene Editing Regulation and Innovation Economics.

Agustina I Whelan, Patricia Gutti, Martin A Lema

Abstract readReview
In one paragraph

Review in Frontiers in bioengineering and biotechnology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Evolution of the Canadian regulatory system for plant biotechnology.Frontiers in bioengineering and biotechnology · 2026
    Article
  3. Genome-Edited Fish in the Field.Current issues in molecular biology · 2025
    Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. Overcoming Obstacles to Gene-Edited Solutions to Climate Challenges.Cold Spring Harbor perspectives in biology · 2024
    Review
  9. Article
  10. Article
  11. Review
  12. 3Bs of CRISPR-Cas mediated genome editing in plants: exploring the basics, bioinformatics and biosafety landscape.Physiology and molecular biology of plants : an international journal of functional plant biology · 2023
    Review
  13. Article
  14. Review
  15. Review
  16. Review
  17. GMOs or non-GMOs? The CRISPR Conundrum.Frontiers in plant science · 2023
    Review
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Agustina I WhelanMaestría en Política y Gestión de la Ciencia y la Tecnología, Universidad de Buenos Aires, Buenos Aires, Argentina.
Patricia GuttiMaestría en Política y Gestión de la Ciencia y la Tecnología, Universidad de Buenos Aires, Buenos Aires, Argentina.
Martin A LemaDirección de Biotecnología, Secretaría de Alimentos y Bioeconomía, Buenos Aires, Argentina.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Argentina was the first country that enacted regulatory criteria to assess if organisms resulting from new breeding techniques (NBTs) are to be regarded as genetically modified organisms (GMOs) or not. The country has now accumulated 4 year of experience applying such criteria, reaching a considerable number of cases, composed mostly of gene-edited plants, animals, and microorganisms of agricultural use. This article explores the effects on economic innovation of such regulatory experience. This is done by comparing the cases of products derived from gene editing and other NBTs that have been presented to the regulatory system, against the cases of GMOs that have been deregulated in the country. Albeit preliminary, this analysis suggests that products from gene editing will have different profiles and market release rates compared with the first wave of products from the so called "modern biotechnology." Gene editing products seems to follow a much faster development rate from bench to market. Such development is driven by a more diverse group of developers, and led mostly by small and medium enterprises (SMEs) and public research institutions. In addition, product profiles are also more diversified in terms of traits and organisms. The inferences of these findings for the agricultural and biotechnology sectors, particularly in developing countries, are discussed.

Indexed as

bioeconomybiotechnology indicatorsbiotechnology regulationCRISPR-CASgene editinggenome editinginnovation economynew breeding techniques

Identifiers

PMID32363186
PMCPMC7181966

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.