Evidence map›Paper›PMID 32363006›Full record

ReviewJournal of oral microbiology2020

Innovative application of nested PCR for detection of

Adrian Brun, Hélène Rangé, Bastien Prouvost, Mikael Mazighi, Yvonne Kapila, Philippe Bouchard, Jean-Baptiste Michel

Open access · goldAbstract readReview
In one paragraph

Review in Journal of oral microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Frontiers in cellular and infection microbiology · 2026
    Article
  3. Review
  4. Association between dental diseases and stroke.The Saudi dental journal · 2024
    Review
  5. Review
  6. The Roles of Periodontal Bacteria in Atherosclerosis.International journal of molecular sciences · 2023
    Review
  7. Oral microbiota in human systematic diseases.International journal of oral science · 2022
    Review
  8. Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Adrian BrunLaboratory for Vascular Translational Science, Inserm UMR_S1148, Paris, France.
Hélène RangéLaboratory Orofacial Pathologies, Imaging and Biotherapies, Université de Paris, Montrouge, France.
Bastien ProuvostDepartment of Periodontology, Service of Odontology, APHP, Rothschild Hospital, Paris, France.
Mikael MazighiLaboratory for Vascular Translational Science, Inserm UMR_S1148, Paris, France.
Yvonne KapilaDepartment of Orofacial Sciences, School of Dentistry, University of California San Francisco, San Francisco, CA, USA.
Philippe BouchardLaboratory Orofacial Pathologies, Imaging and Biotherapies, Université de Paris, Montrouge, France.
Jean-Baptiste MichelLaboratory for Vascular Translational Science, Inserm UMR_S1148, Paris, France.
Hôpital Rothschild · FRAssistance Publique – Hôpitaux de Paris · FRInserm · FRUniversity of California, San Francisco · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atherothrombosis, leading to stroke and myocardial infarction, is responsible for most of the deaths in the world. An increased risk of atherothrombotic vascular events has been reported in patients with periodontitis. Periodontitis is a chronic multifactorial inflammatory disease, which involves a dysbiotic microbiota, and leads to a progressive destruction of the tooth-supporting apparatus. Transcient periodontal pathogen blood translocation, mainly bacteremia, has been associated with the severity of gingival inflammation. The identification of periodontal bacteria within atherothrombotic plaques is challenging and unpredictable. This review aims to summarize existing molecular technics for identifying periodontal microbiota in human atherothrombotic samples. A secondary objective is to describe a protocol for the identification of

Indexed as

16s rRNA geneatherothrombotic plaquesPeriodontal microbiotapolymerase chain reactionPorphyromonas gingivaliswhole genome sequencing

Identifiers

PMID32363006
PMCPMC7178846
OpenAlexW3015780567

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.