Evidence map›Paper›PMID 32362928›Full record

ArticleThe journal of venomous animals and toxins including tropical diseases2020

Venomics and antivenomics of the poorly studied Brazil's lancehead,

Libia Sanz, Alicia Pérez, Sarai Quesada-Bernat, Rafaela Diniz-Sousa, Leonardo A Calderón, Andreimar M Soares, Juan J Calvete, Cleópatra A S Caldeira

Open access · goldAbstract read
In one paragraph

Article in The journal of venomous animals and toxins including tropical diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 22 citations in OpenAlex.

  1. Venomics across theJournal of proteome research · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Crosstalk of Inflammation and Coagulation inInternational journal of molecular sciences · 2023
    Review
  6. Review
  7. Venom characterization of the Brazilian Pampa snake Bothrops pubescens by top-down and bottom-up proteomics.Toxicon : official journal of the International Society on Toxinology · 2022
    Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 3 countries.

Libia SanzEvolutionary and Translational Venomics Laboratory, Spanish National Research Council (CSIC), Valencia, Spain.
Alicia PérezEvolutionary and Translational Venomics Laboratory, Spanish National Research Council (CSIC), Valencia, Spain.
Sarai Quesada-BernatEvolutionary and Translational Venomics Laboratory, Spanish National Research Council (CSIC), Valencia, Spain.
Rafaela Diniz-SousaCenter for the Study of Biomolecules Applied to Health (CEBio), Oswaldo Cruz Foundation Rondônia, Porto Velho, RO, Brazil.
Leonardo A CalderónCenter for the Study of Biomolecules Applied to Health (CEBio), Oswaldo Cruz Foundation Rondônia, Porto Velho, RO, Brazil.
Andreimar M SoaresCenter for the Study of Biomolecules Applied to Health (CEBio), Oswaldo Cruz Foundation Rondônia, Porto Velho, RO, Brazil.
Juan J CalveteEvolutionary and Translational Venomics Laboratory, Spanish National Research Council (CSIC), Valencia, Spain.ORCID 0000-0001-5026-3122
Cleópatra A S CaldeiraCenter for the Study of Biomolecules Applied to Health (CEBio), Oswaldo Cruz Foundation Rondônia, Porto Velho, RO, Brazil.ORCID 0000-0003-1670-5227
Consejo Superior de Investigaciones Científicas · ESUniversidade Federal de Rondônia · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe Brazil's lancehead,

methodsWe have applied a quantitative snake venomics approach, including reverse-phase and two-dimensional electrophoretic decomplexation of the venom toxin arsenal, LC-ESI-MS mass profiling and peptide-centric MS/MS proteomic analysis, to unveil the overall protein composition of

resultsThe venom proteome of the Brazil's lancehead (Pará) is predominantly composed of two major and three minor acidic (19%) and two major and five minor basic (14%) phospholipase A

conclusionThe proteomics outcome contribute to a deeper insight into the spectrum of toxins present in the venom of the Brazil's lancehead, and rationalize the pathophysiology underlying this snake bite envenomings. The comparative qualitative and quantitative immunorecognition profile of the Brazilian pentabothropic antivenom toward the venom toxins of

Indexed as

Bothrops braziliBrazilian antibothropic polyvalent antivenomSnake venomThird-generation antivenomicsVenomics

Identifiers

PMID32362928
PMCPMC7179968
OpenAlexW3017374018

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.