ReviewJournal of visceral surgery2020
Antibiotics alone as an alternative to appendectomy for uncomplicated acute appendicitis in adults: Changes in treatment modalities related to the COVID-19 health crisis.
Review in Journal of visceral surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04440150 (Preoperative Immature Granulocyte Count and Percentage for Complicated and Uncomplicated Appendisitis), which is not on this map. Cited by 57 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Preoperative Immature Granulocyte Count and Percentage for Complicated and Uncomplicated Appendisitis
Who cites it
57 citing papers in PubMed, 101 citations in OpenAlex.
- Epidemiological and histopathological spectrum of gastrointestinal tract disorders: a decade of records from the UAE.BMC gastroenterology · 2025Article
- Retrospective registry-based nationwide analysis of the COVID-19 lockdown effect on the volume of general and visceral non-malignant surgical procedures.Surgery in practice and science · 2024Article
- Navigating appendicitis care during the Covid-19 pandemic: a retrospective cohort study in China.BMC surgery · 2024Article
- The impact of the COVID-19 pandemic on the number of patients presenting with appendicitis to the emergency department.Przeglad gastroenterologiczny · 2024Article
- Effect of the SARS-CoV-2 pandemic on planned and emergency hernia repair in Sweden: a register-based study.Hernia : the journal of hernias and abdominal wall surgery · 2023Article
- Patients with appendicitis during COVID-19 pandemic: a retrospective cohort study.Annals of medicine and surgery (2012) · 2023Article
- Concurrent SARS-COV-19 and acute appendicitis: Management and outcomes across United States children's hospitals.Surgery · 2023Article
- The Course and Surgical Treatment of Acute Appendicitis during the First and Second Wave of the COVID-19 Pandemic: A Retrospective Analysis in University Affiliated Hospital in Latvia.Medicina (Kaunas, Lithuania) · 2023Article
- Exploring the Trends of Acute Appendicitis Following Recovery or Vaccination From COVID-19.The Journal of surgical research · 2022Article
- Impact of the COVID-19 pandemic on hernia surgery in a Swedish healthcare region: a population-based cohort study.BMC surgery · 2022Article
- The effects of COVID-19 pandemic on patients with acute appendicitis.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2022Article
- The effects of COVID-19 pandemic on emergency anterior abdominal wall hernia surgery: is it safe to postpone elective hernia surgery in the pandemic?European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2022Article
- Impact of coronavirus disease on acute appendicitis cases.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2022Article
- The treatment of acute appendicitis in two age-based groups during COVID-19 pandemic: a retrospective experience in a COVID-19 referral hospital.International journal of colorectal disease · 2022Article
- COVID-19 pandemic changed the management and outcomes of acute appendicitis in northern Beijing: A single-center study.World journal of clinical cases · 2022Article
- Delayed diagnosis and subsequently increased severity of acute appendicitis (compatible with clinical-pathologic grounds) during the COVID-19 pandemic: an observational case-control study.BMC gastroenterology · 2022Observational
- Incidence of Complicated Appendicitis during the COVID-19 Pandemic versus the Pre-Pandemic Period: A Systematic Review and Meta-Analysis of 2782 Pediatric Appendectomies.Diagnostics (Basel, Switzerland) · 2022Review
- The Impact of the Coronavirus Disease - 19 Pandemic on the Clinical Characteristics and Treatment of Adult Patients with Acute Appendicitis.Frontiers in surgery · 2022Article
- The Impact of the COVID-19 Pandemic on the Incidence, Severity, and Management of Acute Appendicitis: A Single Center Experience in Thailand.Emergency medicine international · 2022Article
- Article
Corrections and comments
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Authors and funding
7 authors at 6 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The massive inflow of patients with COVID-19 requiring urgent care has overloaded hospitals in France and impacts the management of other patients. Deferring hospitalization and non-urgent surgeries has become a priority for surgeons today in order to relieve the health care system. It is obviously not simple to reduce emergency surgery without altering the quality of care or leading to a loss of chance for the patient. Acute appendicitis is a very specific situation and the prevalence of this disease leads us to reconsider this particular disease in the context of the COVID-19 crisis. Indeed, while the currently recommended treatment for uncomplicated acute appendicitis is surgical appendectomy, the non-surgical alternative of medical management by antibiotic therapy alone has been widely evaluated by high-quality studies in the literature. Insofar as the main limitation of exclusively medical treatment of uncomplicated acute appendicitis is the risk of recurrent appendicitis, this treatment option represents an alternative of choice to reduce the intra-hospital overload in this context of health crisis. The aim of this work is therefore to provide physicians and surgeons with a practical guide based on a review of the literature on the medical treatment of uncomplicated acute appendicitis in adults, to offer this alternative treatment to the right patients and under good conditions, especially when access to the operating room is limited or impossible.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.