Evidence map›Paper›PMID 32362315›Full record

ArticleMolecular cell2020

Mechanistic Insight into Crossing over during Mouse Meiosis.

Shaun E Peterson, Scott Keeney, Maria Jasin

Open access · bronzeAbstract read
In one paragraph

Article in Molecular cell, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 39 citations in OpenAlex.

  1. Article
  2. The Role of theGenes · 2026
    Article
  3. Article
  4. Article
  5. Non-uniform chromosomal SNP density biases sites of meiotic crossovers inbioRxiv : the preprint server for biology · 2025
    Article
  6. Article
  7. Multi-step implementation of meiotic crossover patterning.bioRxiv : the preprint server for biology · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Cell genomics · 2023
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Shaun E PetersonDevelopmental Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Scott KeeneyMolecular Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Howard Hughes Medical Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA. Electronic address: s-keeney@ski.mskcc.org.
Maria JasinDevelopmental Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA. Electronic address: m-jasin@ski.mskcc.org.
Memorial Sloan Kettering Cancer Center · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
Mechanism and regulation of meiotic recombinationR35GM118092 · NIGMS · SLOAN-KETTERING INST CAN RESEARCH · PI Scott Keeney · 2016 to 2026
$7.0M
Homologous recombination mechanisms in mammalian cellsR35GM118175 · NIGMS · SLOAN-KETTERING INST CAN RESEARCH · PI JASIN, MARIA · 2016 to 2020
$2.6M
NCI NIH HHS P30 CA008748NIGMS NIH HHS R35 GM118092NIGMS NIH HHS R35 GM118175
6 · The paper itself

Abstract

Crossover recombination is critical for meiotic chromosome segregation, but how mammalian crossing over is accomplished is poorly understood. Here, we illuminate how strands exchange during meiotic recombination in male mice by analyzing patterns of heteroduplex DNA in recombinant molecules preserved by the mismatch correction deficiency of Msh2

Indexed as

AnimalsChromosome SegregationCrossing Over, GeneticDNA Breaks, Double-StrandedDNA, CruciformDNA RepairHomologous RecombinationMaleMeiosisMiceMice, Inbred DBAMutS Homolog 2 ProteinNucleic Acid HeteroduplexesDNA, CruciformMsh2 protein, mouseMutS Homolog 2 ProteinNucleic Acid Heteroduplexescrossing overcrossoversDNA repairheteroduplex DNAhomology-directed repairmeiosismeiotic recombinationmismatch repairmouserecombination

Identifiers

PMID32362315
PMCPMC7454200
OpenAlexW3023580276

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.