Evidence map›Paper›PMID 32362037›Full record

ArticleProtein science : a publication of the Protein Society2020

Structural and chemical trapping of flavin-oxide intermediates reveals substrate-directed reaction multiplicity.

Kuan-Hung Lin, Syue-Yi Lyu, Hsien-Wei Yeh, Yi-Shan Li, Ning-Shian Hsu, Chun-Man Huang, Yung-Lin Wang, Hao-Wei Shih, Zhe-Chong Wang, Chang-Jer Wu and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Protein science : a publication of the Protein Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Kuan-Hung LinGenomics Research Center, Academia Sinica, Taipei, Taiwan.
Syue-Yi LyuGenomics Research Center, Academia Sinica, Taipei, Taiwan.
Hsien-Wei YehGenomics Research Center, Academia Sinica, Taipei, Taiwan.
Yi-Shan LiGenomics Research Center, Academia Sinica, Taipei, Taiwan.
Ning-Shian HsuGenomics Research Center, Academia Sinica, Taipei, Taiwan.
Chun-Man HuangGenomics Research Center, Academia Sinica, Taipei, Taiwan.
Yung-Lin WangGenomics Research Center, Academia Sinica, Taipei, Taiwan.
Hao-Wei ShihGenomics Research Center, Academia Sinica, Taipei, Taiwan.
Zhe-Chong WangGenomics Research Center, Academia Sinica, Taipei, Taiwan.
Chang-Jer WuDepartment of Food Science, National Taiwan Ocean University, Keelung, Taiwan.
Tsung-Lin LiGenomics Research Center, Academia Sinica, Taipei, Taiwan.ORCID 0000-0002-9739-9761

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Though reactive flavin-N5/C4α-oxide intermediates can be spectroscopically profiled for some flavin-assisted enzymatic reactions, their exact chemical configurations are hardly visualized. Structural systems biology and stable isotopic labelling techniques were exploited to correct this stereotypical view. Three transition-like complexes, the α-ketoacid…N5-FMN

Indexed as

AmycolatopsisBacterial ProteinsCatalytic DomainFlavinsMixed Function OxygenasesOxidation-ReductionBacterial ProteinsFlavinsMixed Function OxygenasesBaeyer-Villiger oxidationflavin mononucleotidemandelate oxidasemonooxygenaseoxidative decarboxylation

Identifiers

PMID32362037
PMCPMC7314388

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.