Evidence map›Paper›PMID 32362025›Full record

ArticleJournal of cardiac surgery2020

Revascularization following non-ST elevation myocardial infarction in multivessel coronary disease.

Lauren V Huckaby, Ibrahim Sultan, Suresh Mulukutla, Dustin Kliner, Thomas G Gleason, Yisi Wang, Floyd Thoma, Arman Kilic

Open access · greenAbstract readComparative Study
In one paragraph

Article in Journal of cardiac surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Review
  5. Percutaneous coronary interventionEuropean journal of translational myology · 2025
    Article
  6. Review
  7. Observational
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Lauren V HuckabyDepartment of Cardiothoracic Surgery, Division of Cardiac Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.
Ibrahim SultanDepartment of Cardiothoracic Surgery, Division of Cardiac Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.ORCID http://orcid.org/0000-0002-1737-4012
Suresh MulukutlaDepartment of Medicine, Division of Cardiology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.
Dustin KlinerDepartment of Medicine, Division of Cardiology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.
Thomas G GleasonDepartment of Cardiothoracic Surgery, Division of Cardiac Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.
Yisi WangDepartment of Cardiothoracic Surgery, Division of Cardiac Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.
Floyd ThomaDepartment of Cardiothoracic Surgery, Division of Cardiac Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.
Arman KilicDepartment of Cardiothoracic Surgery, Division of Cardiac Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.ORCID http://orcid.org/0000-0001-8112-8345
University of Pittsburgh Medical Center · US

Funding

Vascular Surgery Research Training (VascTrain) ProgramT32HL098036 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Edith Tzeng · 2010 to 2026
$7.2M
NHLBI NIH HHS T32 HL098036
6 · The paper itself

Abstract

backgroundThe optimal revascularization approach for patients with multivessel coronary artery disease (MVCAD) is controversial. We sought to investigate outcomes in patients undergoing coronary artery bypass grafting (CABG) or percutaneous coronary intervention (PCI) for non-ST elevation myocardial infarction (NSTEMI).

methodsAdult patients with MVCAD and NSTEMI undergoing either CABG or PCI at a single institution between 2011 and 2018 were included. Multivariable analysis was utilized to determine independent predictors of death, major adverse cardiac and cerebrovascular events (MACCE), and readmissions. A subanalysis examined patients undergoing complete revascularization.

resultsA total of 2001 patients were included, of whom 1480 (74.0%) underwent CABG. CABG was associated with a lower risk-adjusted hazard for death (hazard ratio, 0.59, P < .001) and with improved survival at 1 year (92.0 vs 81.8%, P < .001) and 5 years (80.7 vs 63.3%, P < .001). Additionally, freedom from MACCE (P < .001) was greater in the CABG group and cumulative readmission, rates of MI, and rates of repeat revascularization were lower with CABG (each P < .001). Among patients undergoing complete revascularization, overall survival (1 year: 92.7 vs 83.9%, P = .010; 5 years: 81.1 vs 69.4%, P < .001) and freedom from MACCE (1 year: 92.3 vs 75.2%, P < .001; 5 years: 81.7 vs 61.4%, P < .001) remained higher for the CABG group; cumulative incidence of readmission was also decreased in those undergoing CABG (P < .001).

conclusionsIn this real-world analysis of patients with MVCAD presenting with NSTEMI, revascularization with CABG resulted in improved survival with lower rates of MACCE and readmission as compared to PCI, which persisted when accounting for complete revascularization.

Indexed as

AgedAged, 80 and overCardiovascular DiseasesCerebrovascular DisordersCoronary Artery BypassCoronary DiseaseFemaleHumansMaleMiddle AgedMultivariate AnalysisMyocardial InfarctionPatient ReadmissionPercutaneous Coronary InterventionPostoperative ComplicationsSurvival Ratecoronary artery disease

Identifiers

PMID32362025
PMCPMC9057453
OpenAlexW3022718644

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.