Evidence map›Paper›PMID 32362022›Full record

ArticleJournal of leukocyte biology2020

Integrative analysis of microRNA and mRNA expression profiles of monocyte-derived dendritic cells differentiation during experimental cerebral malaria.

Patrícia Aparecida Assis, Danielle Fernandes Durso, Fernanda Chacon Cavalcante, Ricardo Zaniratto, Ana Carolina Carvalho-Silva, Edecio Cunha-Neto, Douglas Taylor Golenbock, Ludmila Rodrigues Pinto Ferreira, Ricardo Tostes Gazzinelli

Open access · greenAbstract read
In one paragraph

Article in Journal of leukocyte biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Cerebral malaria induced byFrontiers in cellular and infection microbiology · 2022
    Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Patrícia Aparecida AssisDepartment of Pathology, University of Michigan Medical School, Ann Arbor, Michigan, USA.ORCID 0000-0002-4352-7123
Danielle Fernandes DursoDivision of Infectious Diseases and Immunology, University of Massachusetts Medical School, Worcester, Massachusetts, USA.
Fernanda Chacon CavalcanteLaboratory of Immunopathology, Fundação Oswaldo Cruz - Minas, Belo Horizonte, Minas Gerais, Brazil.
Ricardo ZanirattoLaboratory of Immunology, Heart Institute (InCor), University of São Paulo School of Medicine, São Paulo, Brazil.
Ana Carolina Carvalho-SilvaRNA Systems Biology Laboratory (RSBL), Departamento de Morfologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
Edecio Cunha-NetoLaboratory of Immunology, Heart Institute (InCor), University of São Paulo School of Medicine, São Paulo, Brazil.
Douglas Taylor GolenbockDivision of Infectious Diseases and Immunology, University of Massachusetts Medical School, Worcester, Massachusetts, USA.
Ludmila Rodrigues Pinto FerreiraRNA Systems Biology Laboratory (RSBL), Departamento de Morfologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
Ricardo Tostes GazzinelliDivision of Infectious Diseases and Immunology, University of Massachusetts Medical School, Worcester, Massachusetts, USA.
University of Massachusetts Chan Medical School · USUniversidade de São Paulo · BRUniversidade Federal de Minas Gerais · BRFundação Oswaldo Cruz · BRUniversity of Michigan · US

Funding

Sugar-feeding behavior of the malaria vector Nyssorhynchus darlingi and development of effective attractive toxic sugar baits (ATSB) to increase intervention success in PeruU19AI089681 · NIAID · YALE UNIVERSITY · PI CASTRO, MARCIA C. · 2010 to 2023
$20.1M
Innate Immune Activation in MalariaR01AI079293 · NIAID · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI FITZGERALD, KATHERINE A., GOLENBOCK, DOUGLAS T · 2009 to 2024
$10.9M
Monocyte-derived dendritic cells in malariaR01NS098747 · NINDS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI GAZZINELLI, RICARDO TOSTES, LUSTER, ANDREW D · 2016 to 2020
$2.1M
Killing of P. vivax infected reticulocytes by cytotoxic T cellsR21AI131632 · NIAID · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI GAZZINELLI, RICARDO TOSTES, LIEBERMAN, JUDY · 2018 to 2019
$484k
NIAID NIH HHS R01 AI079293NIAID NIH HHS R21 AI131632NIAID NIH HHS U19 AI089681NINDS NIH HHS R01 NS098747
6 · The paper itself

Abstract

Heterogeneity and high plasticity are common features of cells from the mononuclear phagocyte system: monocytes (MOs), macrophages, and dendritic cells (DCs). Upon activation by microbial agents, MO can differentiate into MO-derived DCs (MODCs). In previous work, we have shown that during acute infection with Plasmodium berghei ANKA (PbA), MODCs become, transiently, the main CD11b

Indexed as

AnimalsDendritic CellsGene Expression RegulationMalaria, CerebralMiceMice, KnockoutMicroRNAsMonocytesPlasmodium bergheiRNA, MessengerTranscriptomeMicroRNAsRNA, Messengercell differentiationmiRNAMODCPlasmodiumsystems biology

Identifiers

PMID32362022
PMCPMC11215656
OpenAlexW3021331248

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.