ArticleBrain imaging and behavior2020
Dynamic network connectivity predicts subjective cognitive decline: the Sino-Longitudinal Cognitive impairment and dementia study.
Article in Brain imaging and behavior, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Grey matter changes on brain MRI in subjective cognitive decline: a systematic review.Alzheimer's research & therapy · 2022Pooled it
- Characterizing the progression from mild cognitive impairment to dementia: a network analysis of longitudinal clinical visits.BMC medical informatics and decision making · 2024Article
- Drinking severity mediates the relationship between hypothalamic connectivity and rule-breaking/intrusive behavior differently in young women and men: an exploratory study.Quantitative imaging in medicine and surgery · 2024Article
- Dysfunctions of multiscale dynamic brain functional networks in subjective cognitive decline.Brain communications · 2024Article
- Relationship among number of close friends, subclinical geriatric depression, and subjective cognitive decline based on regional homogeneity of functional magnetic resonance imaging data.Frontiers in aging neuroscience · 2022Article
- Functional Connectivity Dynamics Altered of the Resting Brain in Subjective Cognitive Decline.Frontiers in aging neuroscience · 2022Article
- Disrupted Dynamic Functional Connectivity in Distinguishing Subjective Cognitive Decline and Amnestic Mild Cognitive Impairment Based on the Triple-Network Model.Frontiers in aging neuroscience · 2021Article
- Alterations in Dynamic Functional Connectivity in Individuals With Subjective Cognitive Decline.Frontiers in aging neuroscience · 2021Article
- Plasma β-Amyloid Levels Associated With Structural Integrity Based on Diffusion Tensor Imaging in Subjective Cognitive Decline: The SILCODE Study.Frontiers in aging neuroscience · 2020Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
Subjective cognitive decline (SCD) is the preclinical stage of Alzheimer's disease (AD), the most common neurodegenerative disease in the elderly. We collected resting-state functional MRI data and applied novel graph-theoretical analyses to investigate the dynamic spatiotemporal cerebral connectivities in 63 individuals with SCD and 67 normal controls (NC). Temporal flexibility and spatiotemporal diversity were mapped to reflect dynamic time-varying functional interactions among the brain regions within and outside communities. Temporal flexibility indicates how frequently a brain region interacts with regions of other communities across time; spatiotemporal diversity describes how evenly a brain region interacts with regions belonging to other communities. SCD and NC differed in large-scale brain dynamics characterized by the two measures, which, with support vector machine, demonstrated higher classification accuracies than conventional static parameters and structural metrics. The findings characterize dynamic network dysfunction that may serve as a biomarker of the preclinical stage of AD.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.