Evidence map›Paper›PMID 32361871›Full record

ArticleTechniques in coloproctology2020

Retrospective study of the functional and oncological outcomes of conformal sphincter preservation operation in the treatment of very low rectal cancer.

G Sun, Z Lou, H Zhang, G Y Yu, K Zheng, X H Gao, R G Meng, H F Gong, E J B Furnée, C G Bai and 1 more

Abstract read
In one paragraph

Article in Techniques in coloproctology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

G Sun *Department of Colorectal Surgery, Changhai Hospital, 168 Changhai Rd, Shanghai, 200433, China.
Z Lou *Department of Colorectal Surgery, Changhai Hospital, 168 Changhai Rd, Shanghai, 200433, China.
H ZhangDepartment of Colorectal Surgery, Changhai Hospital, 168 Changhai Rd, Shanghai, 200433, China.
G Y YuDepartment of Colorectal Surgery, Changhai Hospital, 168 Changhai Rd, Shanghai, 200433, China.
K ZhengDepartment of Colorectal Surgery, Changhai Hospital, 168 Changhai Rd, Shanghai, 200433, China.
X H GaoDepartment of Colorectal Surgery, Changhai Hospital, 168 Changhai Rd, Shanghai, 200433, China.
R G MengDepartment of Colorectal Surgery, Changhai Hospital, 168 Changhai Rd, Shanghai, 200433, China.
H F GongDepartment of Colorectal Surgery, Changhai Hospital, 168 Changhai Rd, Shanghai, 200433, China.
E J B FurnéeDepartment of Surgery, University Medical Center Groningen, Groningen, the Netherlands.
C G BaiDepartment of Pathology, Changhai Hospital, Shanghai, China.
W ZhangDepartment of Colorectal Surgery, Changhai Hospital, 168 Changhai Rd, Shanghai, 200433, China. weizhang2000cn@163.com.ORCID 0000-0003-3094-9711

Funding

National Natural Science Foundation of China #81572358, #81572332Science and Technology Commission of Shanghai Municipality SHDC12016122
6 · The paper itself

Abstract

backgroundConformal sphincter preservation operation (CSPO) is a new surgical procedure for very low rectal cancers (within 4-5 cm from the anal verge). CSPO preserves more of the dentate line and distal rectal wall and also avoids injuring nerves in the intersphincteric space, resulting in satisfactory anal function after resection. The aim of this study was to analyze the short-term surgical results and long-term oncological and functional outcomes of CSPO.

methodsConsecutive patients with very low rectal cancer, who had CSPO between January 2011 and October 2018 at Changhai Hospital, Shanghai were included. Patient demographics, clinicopathological features, oncological outcomes and anal function were analyzed.

resultsA total of 102 patients (67 men) with a mean age of 56.9 ± 10.8 years were included. The median distance of the tumor from the anal verge was 3 (IQR, 3-4) cm. Thirty-five patients received neoadjuvant chemoradiation (nCRT). The median distal resection margin (DRM) was 0.5 (IQR, 0.3-0.8) cm. One patient had a positive DRM. All circumferential margins were negative. There was no perioperative mortality. The postoperative complication rate was 19.6%. The median duration of follow-up was 28 (IQR, 12-45.5) months. The local recurrence rate was 2% and distant metastasis rate was 10.8%. The 3-year overall survival and disease-free survival rates were 100% and 83.9%, respectively. The mean Wexner incontinence and low anterior resection syndrome scores 12 months after ileostomy reversal were 5.9 ± 4.3, and 29.2 ± 6.9, respectively.

conclusionsFor patients with very low rectal cancers, fecal continence can be preserved with CSPO without compromising oncological results.

Indexed as

Postoperative ComplicationsRectal NeoplasmsAgedAnal CanalChinaHumansMaleMiddle AgedNeoplasm Recurrence, LocalRetrospective StudiesSyndromeTreatment OutcomeDisease-free survivalFollow-up studiesLocalLow anterior resection syndromeMargins of excisionNeoplasm recurrencePostoperative complicationsRectal neoplasmsSurgery

Identifiers

PMID32361871
PMCPMC7522072

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