ArticleNeuroImage. Clinical2020
Brain function and clinical characterization in the Boston adolescent neuroimaging of depression and anxiety study.
Article in NeuroImage. Clinical, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed.
- A canary in the mind: A single baseline brain scan predicts adolescent depression and anxiety one year later.medRxiv : the preprint server for health sciences · 2026Article
- Tract-explainable and underexplained synchrony play complementary roles in the functional organization of the brain.bioRxiv : the preprint server for biology · 2026Article
- Identifying impulsivity and substance use measures in neuroimaging datasets: A scoping review and searchable dataset repository for researchers.Current addiction reports · 2026Article
- Multimodal Neuroimaging Signature of Sleep Problems Predicts Preadolescent Mental Health Trajectories.medRxiv : the preprint server for health sciences · 2025Article
- Evidence of Disrupted Hippocampal Gray- and White-Matter Development in Adolescent Anxiety Disorders, Independent From Early-Life Stress.Hippocampus · 2025Article
- Prospective Relations between Cortical Thickness and Change in Internalizing Symptoms are Moderated by Chronic Stress Exposure in Adolescents with Depression and Anxiety.Clinical psychological science : a journal of the Association for Psychological Science · 2025Article
- Intrinsic functional brain connectivity in adolescent anxiety: Associations with behavioral phenotypes and cross-syndrome network features.Journal of affective disorders · 2025Article
- Explanatory model of behavioral adaptation in video game addiction among adolescents in urban and rural Peru: the mediating role of anxiety.Frontiers in psychology · 2025Article
- Brain functional connectivity predicts depression and anxiety during childhood and adolescence: A connectome-based predictive modeling approach.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Depression-associated reductions in putaminal volume are accompanied by a shift from matrix-like to striosome-like structural connectivity.Frontiers in psychiatry · 2025Article
- The relationship between childhood trauma and mental health status among Chinese vocational high school adolescents: the mediating effect of poor self-control and internet addiction.BMC public health · 2024Article
- The Human Connectome Project of adolescent anxiety and depression dataset.Scientific data · 2024Article
- Striatal and Behavioral Responses to Reward Vary by Socioeconomic Status in Adolescents.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Reducing default mode network connectivity with mindfulness-based fMRI neurofeedback: a pilot study among adolescents with affective disorder history.Molecular psychiatry · 2023Article
- Connectivity patterns evoked by fearful faces demonstrate reduced flexibility across a shared dimension of adolescent anxiety and depression.Clinical psychological science : a journal of the Association for Psychological Science · 2023Article
- Reward-Related Neural Circuitry in Depressed and Anxious Adolescents: A Human Connectome Project.Journal of the American Academy of Child and Adolescent Psychiatry · 2022Article
- Using diffusion MRI data acquired with ultra-high gradient strength to improve tractography in routine-quality data.NeuroImage · 2021Article
- Convergence, preliminary findings and future directions across the four human connectome projects investigating mood and anxiety disorders.NeuroImage · 2021Article
- Functional Alterations in Cerebellar Functional Connectivity in Anxiety Disorders.Cerebellum (London, England) · 2021Article
- Neural Correlates Associated With Suicide and Nonsuicidal Self-injury in Youth.Biological psychiatry · 2021Review
Corrections and comments
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Authors and funding
24 authors.
Funding
Abstract
We present a Human Connectome Project study tailored toward adolescent anxiety and depression. This study is one of the first studies of the Connectomes Related to Human Diseases initiative and is collecting structural, functional, and diffusion-weighted brain imaging data from up to 225 adolescents (ages 14-17 years), 150 of whom are expected to have a current diagnosis of an anxiety and/or depressive disorder. Comprehensive clinical and neuropsychological evaluations and longitudinal clinical data are also being collected. This article provides an overview of task functional magnetic resonance imaging (fMRI) protocols and preliminary findings (N = 140), as well as clinical and neuropsychological characterization of adolescents. Data collection is ongoing for an additional 85 adolescents, most of whom are expected to have a diagnosis of an anxiety and/or depressive disorder. Data from the first 140 adolescents are projected for public release through the National Institutes of Health Data Archive (NDA) with the timing of this manuscript. All other data will be made publicly-available through the NDA at regularly scheduled intervals. This article is intended to serve as an introduction to this project as well as a reference for those seeking to clinical, neurocognitive, and task fMRI data from this public resource.
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