ArticleMedical hypotheses2020
Airborne route and bad use of ventilation systems as non-negligible factors in SARS-CoV-2 transmission.
Article in Medical hypotheses, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 113 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
113 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A systematic review and meta-analysis of indoor bioaerosols in hospitals: The influence of heating, ventilation, and air conditioning.PloS one · 2021Pooled it
- Article
- Designing Infection-Resilient Cruise Ships: Architectural & Digital Health Strategies.EcoHealth · 2026Article
- Indoor air quality and airborne transmission under the One Health lens: A scoping review.One health (Amsterdam, Netherlands) · 2025Review
- Effectiveness and acceptability of ventilation modifications in healthcare facilities, Liberia 2022-2023.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2025Article
- Review
- Symptom propagation in respiratory pathogens of public health concern: a review of the evidence.Journal of the Royal Society, Interface · 2024Review
- COVID-19 transmission and control in land public transport: A literature review.Fundamental research · 2024Review
- [The structural and spatial design of German intensive care units from the point of view of infection control measures : Survey among ICU-KISS participants].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2024Article
- Drug repurposing of FDA-approved anti-viral drugs via computational screening against novel 6M03 SARS-COVID-19.Irish journal of medical science · 2024Article
- Pertussis seasonal variation in Northern Vietnam: the evidence from a tertiary hospital.BMC public health · 2024Article
- Assessing ventilation through ambient carbon dioxide concentrations across multiple healthcare levels in Ghana.PLOS global public health · 2024Article
- Development of optimal indoor air disinfection and ventilation protocols for airborne infectious diseases.PloS one · 2024Article
- Peak risk of SARS-CoV-2 infection within 5 s of face-to-face encounters: an observational/retrospective study.Scientific reports · 2023Observational
- Energy efficient ventilation and indoor air quality in the context of COVID-19 - A systematic review.Renewable & sustainable energy reviews · 2023Review
- Combined Infection Control Interventions Protect Essential Food Workers from Occupational Exposures to SARS-CoV-2 in the Agricultural Environment.Applied and environmental microbiology · 2023Article
- RT-qPCR-Based Assessment of the Efficacy of 222 nm UVC Irradiation in Reducing SARS-CoV-2 Surface Contamination.Sensors (Basel, Switzerland) · 2023Article
- The Seroprevalence of Hepatitis A in Patients with Positive Human Immunodeficiency Virus.Middle East journal of digestive diseases · 2023Article
- Implemented indoor airborne transmission mitigation strategies during COVID-19: a systematic review.Journal of environmental health science & engineering · 2023Review
- Airborne influenza virus shedding by patients in health care units: Removal mechanisms affecting virus transmission.PloS one · 2023Article
53 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The world is facing a pandemic of unseen proportions caused by a corona virus named SARS-CoV-2 with unprecedent worldwide measures being taken to tackle its contagion. Person-to-person transmission is accepted but WHO only considers aerosol transmission when procedures or support treatments that produce aerosol are performed. Transmission mechanisms are not fully understood and there is evidence for an airborne route to be considered, as the virus remains viable in aerosols for at least 3 h and that mask usage was the best intervention to prevent infection. Heating, Ventilation and Air Conditioning Systems (HVAC) are used as a primary infection disease control measure. However, if not correctly used, they may contribute to the transmission/spreading of airborne diseases as proposed in the past for SARS. The authors believe that airborne transmission is possible and that HVAC systems when not adequately used may contribute to the transmission of the virus, as suggested by descriptions from Japan, Germany, and the Diamond Princess Cruise Ship. Previous SARS outbreaks reported at Amoy Gardens, Emergency Rooms and Hotels, also suggested an airborne transmission. Further studies are warranted to confirm our hypotheses but the assumption of such way of transmission would cause a major shift in measures recommended to prevent infection such as the disseminated use of masks and structural changes to hospital and other facilities with HVAC systems.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.