ArticleNeuroImage. Clinical2020
L-dopa treatment increases oscillatory power in the motor cortex of Parkinson's disease patients.
Article in NeuroImage. Clinical, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
32 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Genome-Wide Meta-Analysis of Parkinson's Disease Associated Genetic Loci and Validation of Therapeutic Targets.Brain and behavior · 2025Pooled it
- Using Magnetoencephalography to Advance the Science of Parkinson Disease: A Systematic Review.Brain and behavior · 2025Pooled it
- Neurophysiological effects of transcranial alternating current stimulation combined with multidisciplinary rehabilitation in Parkinson's disease.Frontiers in psychiatry · 2026Trial
- Fixed-Sequence OFF-to-ON Differences in Low-Beta State Dynamics in Parkinson's Disease: A Paired Source-Space Resting-State EEG Study.Brain topography · 2026Article
- Natural Frequencies of Levodopa-Induced Dyskinesia in Parkinson's Disease.Annals of clinical and translational neurology · 2026Article
- Parkinsonism disrupts the population-level organization of cortical dynamics.bioRxiv : the preprint server for biology · 2026Article
- Normative modeling of MEG brain oscillations across the human lifespan.Communications biology · 2026Article
- Magnetoencephalography-based prediction of longitudinal symptom progression in Parkinson's disease.NPJ Parkinson's disease · 2026Article
- Excessive daytime sleepiness in parkinsonism is associated with cortical and basal ganglia beta oscillatory activity.Communications biology · 2026Article
- A meta-analysis of periodic and aperiodic electrophysiological features in Parkinson's disease.Brain communications · 2026Review
- Dynamic, state-dependent characteristics of cognitive fluctuations in Lewy body dementia: a magnetoencephalography study.Brain communications · 2026Article
- Alterations in beta oscillatory activity occur with the emergence of parkinsonian motor signs across the basal ganglia-thalamocortical network.Neurobiology of disease · 2025Article
- The association between infant EEG aperiodic exponent and the trajectory of restricted and repetitive behaviors for toddlers with and without autism.Journal of neurodevelopmental disorders · 2025Article
- Cortical Effects of Dopamine Replacement Account for Clinical Response Variability in Parkinson's Disease.Movement disorders : official journal of the Movement Disorder Society · 2025Article
- Modulatory effect of levodopa on the basal ganglia-cerebellum connectivity in Parkinson's disease.NPJ Parkinson's disease · 2025Article
- Subthalamic Nucleus Deep Brain Stimulation in the Beta Frequency Range Boosts Cortical Beta Oscillations and Slows Down Movement.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Changes in sensorimotor network dynamics in resting-state recordings in Parkinson's disease.Brain communications · 2025Article
- Deep Brain Stimulation restores information processing in parkinsonian cortical networks.medRxiv : the preprint server for health sciences · 2024Article
- Dysfunction of motor cortices in Parkinson's disease.Cerebral cortex (New York, N.Y. : 1991) · 2024Review
- Mathematical derivation and mechanism analysis of beta oscillations in a cortex-pallidum model.Cognitive neurodynamics · 2024Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
Parkinson's disease (PD) is a movement disorder caused by dopaminergic neurodegeneration. Levodopa (L-dopa) is an effective medication for alleviating motor symptoms in PD that has been shown previously to reduce subcortical beta (13-30 Hz) oscillations. How L-dopa influences oscillations in the motor cortex is unclear. In this study, 21 PD patients were recorded with magnetoencephalography (MEG) in L-dopa ON and OFF states. Oscillatory components of resting-state power spectra were compared between the two states and the significant effect was localized using beamforming. Unified Parkinson's Disease Rating Scale (UPDRS) III akinesia and rigidity sub-scores for the most affected hemibody were correlated with source power values for the contralateral hemisphere. An L-dopa-induced power increase was found over the central sensors significant in the 18-30 Hz range (F
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.