Evidence map›Paper›PMID 32360379›Full record

ArticleProtein expression and purification2020

High-yield production in E. coli and characterization of full-length functional p13

Elka R Georgieva, Peter P Borbat, Christina Fanouraki, Jack H Freed

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Protein expression and purification, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Elka R GeorgievaDepartment of Chemistry and Chemical Biology, Baker Laboratory, Cornell University, Ithaca, NY, 14853, USA. Electronic address: erg54@cornell.edu.
Peter P BorbatDepartment of Chemistry and Chemical Biology, Baker Laboratory, Cornell University, Ithaca, NY, 14853, USA; ACERT Center for Advanced ESR Technology, Cornell University, Ithaca, NY, 14853, USA.
Christina FanourakiDepartment of Chemistry and Chemical Biology, Baker Laboratory, Cornell University, Ithaca, NY, 14853, USA.
Jack H FreedDepartment of Chemistry and Chemical Biology, Baker Laboratory, Cornell University, Ithaca, NY, 14853, USA; ACERT Center for Advanced ESR Technology, Cornell University, Ithaca, NY, 14853, USA.
Cornell University · US

Funding

TR&D 4 for ACERT, 2017-2021 funding periodP41GM103521 · NIGMS · CORNELL UNIVERSITY · PI FREED, JACK H · 2012 to 2021
$11.7M
Electron Spin Relaxation in Model MembranesR01GM123779 · NIGMS · CORNELL UNIVERSITY · PI FREED, JACK H · 2017 to 2020
$2.1M
Production and functional characterization of the L-lysine exporters from bacterial pathogensR03AI137735 · NIAID · CORNELL UNIVERSITY · PI GEORGIEVA, ELKA R · 2018 to 2019
$164k
NIAID NIH HHS R03 AI137735NIGMS NIH HHS P41 GM103521NIGMS NIH HHS R01 GM123779
6 · The paper itself

Abstract

Human T-cell leukemia virus type 1 is an oncovirus that causes aggressive adult T-cell leukemia but is also responsible for severe neurodegenerative and endocrine disorders. Combatting HTLV-1 infections requires a detailed understanding of the viral mechanisms in the host. Therefore, in vitro studies of important virus-encoded proteins would be critical. Our focus herein is on the HTLV-1-encoded regulatory protein p13

Indexed as

Escherichia coliRetroviridae ProteinsHumansHuman T-lymphotropic virus 1Recombinant ProteinsRecombinant ProteinsRetroviridae Proteinsrof protein, Human T-lymphotropic virus 1DEER-detected p13(II) self-associationFluorescence-based p13(II) liposome uptake assayHigh-yield protein productionHuman T-cell leukemia virus type 1 encoded protein p13(II)Viral protein-mitochondrial membrane association

Identifiers

PMID32360379
PMCPMC7266171
OpenAlexW3023059470

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.