Evidence map›Paper›PMID 32360133›Full record

ArticleDigestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver2020

Screening for active COVID-19 infection and immunization status prior to biologic therapy in IBD patients at the time of the pandemic outbreak.

Fabiana Zingone, Andrea Buda, Edoardo Vincenzo Savarino

Open access · bronzeAbstract read
In one paragraph

Article in Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.5field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Review
  3. Critical appraisal of the mechanisms of gastrointestinal and hepatobiliary infection by COVID-19.American journal of physiology. Gastrointestinal and liver physiology · 2021
    Article
  4. Is SARS-CoV-2 screening test indicated for psoriasis patients candidate to biologic therapy?Journal of the European Academy of Dermatology and Venereology : JEADV · 2021
    Article
  5. Review
  6. Article
  7. SARS-CoV-2 infection in severe pediatric Crohn's disease. What about anti-tumor necrosis factor α therapy?Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver · 2020
    Article
  8. No need of transforming gastroenterology units to covid units at the time of SARS-COV2 infection - a single-center analysis from northern italy.Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver · 2020
    Article
  9. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Fabiana ZingoneDivision of Gastroenterology, Department of Surgery, Oncology and Gastroenterology, University of Padua, Italy.
Andrea BudaGastroenterology Unit, Department of Gastrointestinal Oncological Surgery, S.Maria del Prato Hospital, Feltre, Italy.
Edoardo Vincenzo SavarinoDivision of Gastroenterology, Department of Surgery, Oncology and Gastroenterology, University of Padua, Italy. Electronic address: edoardo.savarino@unipd.it.
University of Padua · ITHospital of Prato · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coronavirus disease 2019 has been recently classified as pandemic infection by the World Health Organization. Patients with inflammatory bowel disease (IBD) are invited to follow the national recommendations as any other person. It is unclear whether a more aggressive clinical course might develop in asymptomatic COVID-19 infected subjects during biological therapy and current evidence does not support treatment suspension. However, during pandemic, the start of treatment with immunosuppressive drugs and biologics should be postponed whenever possible and based on an individual risk assessment. When clinical conditions and the disease activity do not allow a treatment delay, before starting a biological therapy, screening of IBD patients for COVID-19 active infection by RT-PCR should be advisable, even in absence of clinical suspicion. Serum antibody testing, when available, could provide evidence of infection as well as identify patients already immune to the disease.

Indexed as

Biological TherapyCoronavirus InfectionsImmunosuppressive AgentsInflammatory Bowel DiseasesPandemicsPneumonia, ViralBetacoronavirusCOVID-19Diagnostic Screening ProgramsHumansImmunizationInfection ControlItalyPatient AcuityRisk AssessmentSARS-CoV-2Immunosuppressive AgentsBiologicCOVID-19Crohn's diseaseIBDscreeningUlcerative Colitis

Identifiers

PMID32360133
PMCPMC7151446
OpenAlexW3015865226

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.