Evidence map›Paper›PMID 32359937›Full record

ArticleBrachytherapy

COVID-19 impact on timing of brachytherapy treatment and strategies for risk mitigation.

Vonetta M Williams, Jenna M Kahn, Matthew M Harkenrider, Junzo Chino, Jonathan Chen, L Christine Fang, Emily F Dunn, Emma Fields, Jyoti S Mayadev, Ramesh Rengan and 2 more

Abstract read
In one paragraph

Article in Brachytherapy. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
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  5. Observational
  6. Gynecologic radiation therapy in low and middle income countries during the COVID-19 pandemic.International journal of gynecological cancer : official journal of the International Gynecological Cancer Society · 2022
    Review
  7. Article
  8. Article
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  10. Impact of COVID-19 on public's interest in radiotherapy and other cancer treatments: a cross-sectional Google Trends analysis.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2022
    Article
  11. Radiotherapy during the COVID-19: a review about management and treatment strategies.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Vonetta M WilliamsDepartment of Radiation Oncology, University of Washington, Seattle, WA.
Jenna M KahnDepartment of Radiation Oncology, Oregon Health & Science University, Portland, OR.
Matthew M HarkenriderDepartment of Radiation Oncology, Loyola University Medical Center, Maywood, IL.
Junzo ChinoDepartment of Radiation Oncology, Duke University, Durham, VA.
Jonathan ChenDepartment of Radiation Oncology, University of Washington, Seattle, WA.
L Christine FangDepartment of Radiation Oncology, University of Washington, Seattle, WA.
Emily F DunnDepartment of Radiation Oncology, Willamette Valley Cancer Institute and Research Center, Eugene, OR.
Emma FieldsDepartment of Radiation Oncology, Virginia Commonwealth University, Richmond, VA.
Jyoti S MayadevDepartment of Radiation Medicine and Applied Sciences, University of California San Diego, La Jolla, CA.
Ramesh RenganDepartment of Radiation Oncology, University of Washington, Seattle, WA.
Daniel PetereitDepartment of Radiation Oncology, Monument Health Cancer Care Institute, Rapid City, SD.
Brandon A DyerDepartment of Radiation Oncology, University of Washington, Seattle, WA. Electronic address: badyer@uw.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe purpose of this study was to highlight the importance of timely brachytherapy treatment for patients with gynecologic, breast, and prostate malignancies, and provide a framework for brachytherapy clinical practice and management in response to the COVID-19 pandemic. METHODS AND MATERIALS: We review amassing evidence to help guide the management and timing of brachytherapy for gynecologic, breast, and prostate cancers. Where concrete data could not be found, peer-reviewed expert opinion is provided.

resultsThere may be a significant negative impact on oncologic outcomes for patients with gynecologic malignancies who have a delay in the timely completion of therapy. Delay of prostate or breast cancer treatment may also impact oncologic outcomes. If a treatment delay is expected, endocrine therapy may be an appropriate temporizing measure before delivery of radiation therapy. The use of shorter brachytherapy fractionation schedules will help minimize patient exposure and conserve resources.

conclusionsBrachytherapy remains a critical treatment for patients and may shorten treatment time and exposure for some. Reduced patient exposure and resource utilization is important during COVID-19. Every effort should be made to ensure timely brachytherapy delivery for patients with gynecologic malignancies, and endocrine therapy may help temporize treatment delays for breast and prostate cancer patients. Physicians should continue to follow developing institutional, state, and federal guidelines/recommendations as challenges in delivering care during COVID-19 will continue to evolve.

Indexed as

BrachytherapyPandemicsBetacoronavirusBreast NeoplasmsCoronavirus InfectionsCOVID-19Dose Fractionation, RadiationFemaleGenital Neoplasms, FemaleHumansMalePneumonia, ViralProstatic NeoplasmsSARS-CoV-2Time-to-TreatmentBrachytherapyBreast cancerCervical cancerCoronavirusCOVID-19COVID19Prostate cancerRadiation oncologyRadiotherapyUterine cancer

Identifiers

PMID32359937
PMCPMC7172676

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.