Evidence map›Paper›PMID 32359475›Full record

ReviewTrends in molecular medicine2020

FABP4: A New Player in Obesity-Associated Breast Cancer.

Jun Zeng, Edward R Sauter, Bing Li

Open access · greenAbstract readReview
In one paragraph

Review in Trends in molecular medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 82 citations in OpenAlex.

  1. Review
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  10. The Transcriptomic Profile Underlying Somatic MonoallelicDiagnostics (Basel, Switzerland) · 2025
    Article
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  13. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Jun ZengSchool of Basic Medical Sciences, Guangzhou Medical University, Guangzhou, China; Department of Microbiology and Immunology, School of Medicine, University of Louisville, Louisville, KY, USA.
Edward R SauterDivision of Cancer Prevention, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
Bing LiDepartment of Microbiology and Immunology, School of Medicine, University of Louisville, Louisville, KY, USA. Electronic address: b.li@louisville.edu.
University of Louisville · USNational Institutes of Health · US

Funding

Prevention of Breast Cancer Development by Epidermal Fatty Acid Binding Protein (R01CA180986 · NCI · UNIVERSITY OF MINNESOTA · PI LI, BING · 2014 to 2025
$3.3M
Immunomodulatory mechanisms of E-FABP in psoriasis pathogenesisR01AI137324 · NIAID · UNIVERSITY OF LOUISVILLE · PI LI, BING · 2018 to 2022
$1.9M
The role of adipocyte/macrophage fatty acid binding protein in breast cancer deveR01CA177679 · NCI · UNIVERSITY OF MINNESOTA · PI LI, BING · 2014 to 2018
$1.6M
NCI NIH HHS R01 CA177679NCI NIH HHS R01 CA180986NIAID NIH HHS R01 AI137324
6 · The paper itself

Abstract

Obesity is known to increase breast cancer incidence and mortality, but the underlying mechanisms remain unsolved. Recent studies demonstrate that adipose fatty acid binding protein (FABP4) promotes obesity-associated breast cancer development, thus suggesting FABP4 as a novel player linking obesity and breast cancer risk.

Indexed as

Breast NeoplasmsFatty Acid-Binding ProteinsFemaleHumansObesityFABP4 protein, humanFatty Acid-Binding ProteinsAdipose fatty acid binding proteinBreast cancerObesityTumor associated macrophages

Identifiers

PMID32359475
PMCPMC7646254
OpenAlexW3016046838

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.