Evidence map›Paper›PMID 32359372›Full record

ReviewWorld journal of surgical oncology2020

Successful pregnancy after complete resection of leiomyomatosis peritonealis disseminate without recurrence:a case report with next-generation sequencing analysis and literature review.

Hualei Bu, Chengjuan Jin, Yan Fang, Yana Ma, Xiao Wang, Jingying Chen, Lijun Chen

Open access · goldAbstract readCase ReportsReview
In one paragraph

Review in World journal of surgical oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.0field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. A rare case of numerous parasitic myomas after laparoscopic myomectomy.The journal of obstetrics and gynaecology research · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Hualei BuDepartment of Obstetrics and Gynecology, Qilu Hospital of Shandong University, 107 Wenhua Xi Road, Jinan, 250012, People's Republic of China.
Chengjuan JinDepartment of Obstetrics and Gynecology, Shanghai General Hospital, School of Medicine, Shanghai Jiao Tong University, 650 XinSongjiang Road, Shanghai, 201620, People's Republic of China.
Yan FangDepartment of Obstetrics and Gynecology, Qilu Hospital of Shandong University, 107 Wenhua Xi Road, Jinan, 250012, People's Republic of China.
Yana MaDepartment of Obstetrics and Gynecology, Qilu Hospital of Shandong University, 107 Wenhua Xi Road, Jinan, 250012, People's Republic of China.
Xiao WangDepartment of Pathology, Qilu Hospital of Shandong University, 107 Wenhua Xi Road, Jinan, 250012, People's Republic of China.
Jingying ChenDepartment of Obstetrics and Gynecology, Qilu Hospital of Shandong University, 107 Wenhua Xi Road, Jinan, 250012, People's Republic of China.
Lijun ChenDepartment of Obstetrics and Gynecology, Qilu Hospital of Shandong University, 107 Wenhua Xi Road, Jinan, 250012, People's Republic of China. qllijunchen@163.com.ORCID http://orcid.org/0000-0002-6048-7434
Qilu Hospital of Shandong University · CNShanghai Jiao Tong University · CN

Funding

grants from the Department of Medical and Health Science Technology of Shandong province 2016WS0345National Natural Science Foundation of China 81602286
6 · The paper itself

Abstract

backgroundPeritoneal leiomyomatosis disseminate (LPD) is a rare disease characterized by widespread dissemination of leiomyomas nodules throughout the peritoneal and omental surfaces. Reports of pregnancy with LPD are even rarer. Therefore, there is no clear consensus on the treatment of LPD on pregnancy, and the pathogenesis is still unclear. CASE PRESENTATION: We reported a case of LPD patient who developed during pregnancy. The patient underwent a cesarean section at 32 weeks of gestation while removing all visible tumors, and no LPD lesions were seen in the subsequent cesarean section at full term. NGS of LPD lesions detected 4 mutations with focal high-level amplifications of CDK4 (cyclin-dependent kinases 4), NBN (Nibrin), DAXX (death domain associated protein), and MYC (myelocytomatosis oncogene). Immunohistochemistry staining analysis among benign leiomyoma, LPD, and leiomyosarcoma verified that LPD was an unusual intermediate between benign and malignant uterine smooth muscle tumors. Besides, LPD is a hormonal-dependent leiomyoma. After a detailed literature search, we summarized the detailed clinical features and follow-up information of patients with LPD during pregnancy.

conclusionsThis is the first reported LPD case of successful term pregnancy without recurrence, following resection of all visible lesions in a prior pregnancy. LPD is an unusual intermediate between benign and malignant uterine smooth muscle tumors.

Indexed as

AdultBiomarkers, TumorCell Cycle ProteinsCesarean SectionCo-Repressor ProteinsCyclin-Dependent Kinase 4DNA Mutational AnalysisFemaleHigh-Throughput Nucleotide SequencingHumansLeiomyomatosisMagnetic Resonance ImagingMolecular ChaperonesMutationNuclear ProteinsPeritoneal NeoplasmsBiomarkers, TumorCDK4 protein, humanCell Cycle ProteinsCo-Repressor ProteinsCyclin-Dependent Kinase 4DAXX protein, humanMolecular ChaperonesMYC protein, humanNBN protein, humanNuclear ProteinsProto-Oncogene Proteins c-mycLeiomyosarcomaLPDNGSPregnancyThe authors Hualei Bu and Chengjuan Jin contributed equally to this work.

Identifiers

PMID32359372
PMCPMC7196235
OpenAlexW3023864678

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.