ArticleJournal of ovarian research2020
Effects of the sperm DNA fragmentation index on the clinical and neonatal outcomes of intracytoplasmic sperm injection cycles.
Article in Journal of ovarian research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 20 citations in OpenAlex.
- Longitudinal semen parameter assessments and live birth: variability and implications for treatment strategies.Fertility and sterility · 2022Trial
- Intracytoplasmic Sperm Injection Clinical Outcomes: A Non-Inferiority Comparison of The Novel Felix™ Electrophoretic System and Conventional Density Gradient Centrifugation for Sperm Selection, A Prospective Clinical Trial.International journal of fertility & sterility · 2026Article
- Association of sperm DNA fragmentation index with semen quality and ART outcomes: real-world evidence from a retrospective cohort.Basic and clinical andrology · 2026Article
- Parental Characteristics Associated With Children Born With Neural Tube Defects in Puebla, Mexico.Cureus · 2025Article
- Sperm DNA fragmentation index did not associate with assisted reproductive outcomes: a cohort retrospective study of 5784 IVF/ICSI cycles.Journal of assisted reproduction and genetics · 2025Article
- Sperm DNA fragmentation index: limited effectiveness on predicting embryo quality in assisted reproduction technology treatments.Reproductive biology and endocrinology : RB&E · 2025Article
- Article
- Sperm DNA fragmentation index affect pregnancy outcomes and offspring safety in assisted reproductive technology.Scientific reports · 2024Article
- Elevated Sperm DNA Damage in IVF-ICSI Treatments Is Not Related to Pregnancy Complications and Adverse Neonatal Outcomes.Journal of clinical medicine · 2023Article
- Correlation analysis of sperm DNA fragmentation index with semen parameters and the effect of sperm DFI on outcomes of ART.Scientific reports · 2023Article
- Does sperm DNA fragmentation affect clinical outcomes during vitrified-warmed single-blastocyst transfer cycles? A retrospective analysis of 2034 vitrified-warmed single-blastocyst transfer cycles.Journal of assisted reproduction and genetics · 2022Article
- Magnetic-Activated Cell Sorting as a Method to Improve Necrozoospermia-Related Asthenozoospermic Samples.Journal of clinical medicine · 2022Article
- A dietary score representing the overall relation of men's diet with semen quality in relation to outcomes of infertility treatment with assisted reproduction.F&S reports · 2021Article
- Sperm morphology and DNA fragmentation after zona pellucida selection.Reproduction & fertility · 2021Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
backgroundMost studies have mainly focused on the effects of the sperm DNA fragmentation index (DFI) on fertilization, embryonic developmental potential and aneuploidy, pregnancy and abortion rates after in vitro fertilization (IVF)/intracytoplasmic sperm injection (ICSI) and have remained controversial. However, few studies have reported the effects of sperm DFI on neonatal outcomes, including stillbirths, neonatal deaths, sex, gestational age, prematurity, birthweight, low birth weight (LBW) and birth defects in newborns. Our objective was to evaluate the effects of sperm DFI on the clinical and neonatal outcomes of ICSI cycles.
methodsThis retrospective study analysed a total of 2067 oocyte retrieval, 1139 transfer and 713 delivery cycles from conventional ICSI cycles, including 301, 469, and 214 live-born infants in groups segregated according to sperm DFI as the < 15%, 15-30% and > 30% groups, respectively. The clinical and neonatal outcomes were compared among the three groups.
resultsSperm DFI did not significantly affect the rates of fertilization, clinical pregnancy, miscarriage or ongoing pregnancy. Sperm DFI did not increase the risk of stillbirths or neonatal deaths. The rates of stillbirths and neonatal deaths were not significantly different among the three groups. The sex, gestational age, prematurity, birthweight and LBW of newborns in the three groups were not significantly affected by sperm DFI. Moreover, sperm DFI did not increase the number of birth defects in children.
conclusionsSperm DFI did not affect the clinical or neonatal outcomes of ICSI cycles.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.