Article in The Journal of physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literature
Who cites it
6 citing papers in PubMed, 8 citations in OpenAlex.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
13 authors at 4 institutions in 4 countries.
Jin-Lin WangKey Laboratory of Molecular Biophysics of Ministry of Education, School of Life Science & Technology, Huazhong University of Science & Technology, Wuhan, Hubei, 430074, China.ORCID 0000-0003-1625-8092
Xiao-Yu WangKey Laboratory of Molecular Biophysics of Ministry of Education, School of Life Science & Technology, Huazhong University of Science & Technology, Wuhan, Hubei, 430074, China.ORCID 0000-0003-1698-3219
Deng-Ke WangDepartment of Physiology and Biophysics, Department of Medicine, Department of Biochemistry, Case Western Reserve University School of Medicine, Cleveland, OH, 44106, USA.
Mark D ParkerDepartment of Physiology and Biophysics, Department of Medicine, Department of Biochemistry, Case Western Reserve University School of Medicine, Cleveland, OH, 44106, USA.ORCID 0000-0003-1761-5282
Raif Musa-AzizDepartment of Physiology and Biophysics, Department of Medicine, Department of Biochemistry, Case Western Reserve University School of Medicine, Cleveland, OH, 44106, USA.
Jacob PoppleDepartment of Physiology and Biophysics, Department of Medicine, Department of Biochemistry, Case Western Reserve University School of Medicine, Cleveland, OH, 44106, USA.ORCID 0000-0001-7257-3690
Yi-Min GuoKey Laboratory of Molecular Biophysics of Ministry of Education, School of Life Science & Technology, Huazhong University of Science & Technology, Wuhan, Hubei, 430074, China.
Tian-Xin MinKey Laboratory of Molecular Biophysics of Ministry of Education, School of Life Science & Technology, Huazhong University of Science & Technology, Wuhan, Hubei, 430074, China.
Tian XiaKey Laboratory of Molecular Biophysics of Ministry of Education, School of Life Science & Technology, Huazhong University of Science & Technology, Wuhan, Hubei, 430074, China.
Min TanSchool of Optical & Electronic Information, Huazhong University of Science & Technology, Wuhan, 430074, China.
Ying LiuKey Laboratory of Molecular Biophysics of Ministry of Education, School of Life Science & Technology, Huazhong University of Science & Technology, Wuhan, Hubei, 430074, China.ORCID 0000-0002-4218-6283
Walter F BoronDepartment of Physiology and Biophysics, Department of Medicine, Department of Biochemistry, Case Western Reserve University School of Medicine, Cleveland, OH, 44106, USA.ORCID 0000-0003-4741-7287
Li-Ming ChenKey Laboratory of Molecular Biophysics of Ministry of Education, School of Life Science & Technology, Huazhong University of Science & Technology, Wuhan, Hubei, 430074, China.ORCID 0000-0002-8129-9563
Huazhong University of Science and Technology · CNUniversity School · USUniversidade de São Paulo · BRWuhan National Laboratory for Optoelectronics · CN
Funding
Multi-scale modeling of gas transport through channels in living cellsU01GM111251 · NIGMS · CASE WESTERN RESERVE UNIVERSITY · PI BORON, WALTER F, SOMERSALO, ERKKI JAAKKO · 2015 to 2019
$2.9M
Role of RPTP-gamma in sensing and transducing acid-base disturbances in the renal proximal tubuleR01DK113197 · NIDDK · CASE WESTERN RESERVE UNIVERSITY · PI BORON, WALTER F · 2017 to 2020
key pointsThe roles of the Na ABSTRACT: The medullary thick ascending limb (mTAL) plays a key role in urinary acid and NaCl excretion. NBCn1 and NBCn2 are present in the basolateral mTAL, where NBCn1 promotes NH
Indexed as
AcidosisLoop of HenleAnimalsBicarbonatesRatsSodiumSodium-Bicarbonate SymportersBicarbonatesSodiumSodium-Bicarbonate Symportersammonium transportHCO3- reabsorptionhypertensionmetabolic acidosismetabolic alkalosisNaCl reabsorption
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Multiple acid-base and electrolyte disturbances upregulate NBCn1, NBCn2, IRBIT and L-IRBIT in the mTAL. · full record | OpenQuestion