ArticleJournal of ultrasound2021
Evaluation of diaphragm thickening by diaphragm ultrasonography: a reproducibility and a repeatability study.
Article in Journal of ultrasound, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07667608 (Ultrasound Assessment of Diaphragmatic Structure and Function in Patients With Liver Cirrhosis), which is not on this map. Cited by 20 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Ultrasound Assessment of Diaphragmatic Structure and Function in Patients With Liver Cirrhosis: A Point-of-Care Tool for Predicting Complications and Sarcopenia in Limited Resource Settings
Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Weaning from mechanical ventilation in ICU patients: research hotspots and trends in the past decade-a bibliometric analysis.Frontiers in medicine · 2026Pooled it
- Reliability and validity of ultrasonography in evaluating the thickness, excursion, stiffness, and strain rate of respiratory muscles in non-hospitalized individuals: a systematic review.BMC oral health · 2023Pooled it
- Association between thoracic ultrasound findings and respiratory function in children with Duchenne muscular dystrophy.European journal of pediatrics · 2026Article
- Intra- and Inter-examiner Reliability of Diaphragmatic Ultrasound Parameters in People with Stable Chronic Obstructive Pulmonary Disease.Physical therapy research · 2026Article
- Intra- and inter-tester reliability of diaphragm thickness and excursion measurements of healthy women using rehabilitative ultrasound imaging across novice examiners.European journal of translational myology · 2025Article
- Diaphragmatic ultrasonography: reference values and reliability for thickness, thickening fraction, and excursion in neonates.European journal of pediatrics · 2025Article
- The Perception of the Diaphragm with Ultrasound: Always There Yet Overlooked?Life (Basel, Switzerland) · 2025Review
- Relationship Between Diaphragm Function and Sarcopenia Assessed by Ultrasound: A Cross-Sectional Study.Diagnostics (Basel, Switzerland) · 2025Article
- Robotic Ultrasound Scanning End-Effector with Adjustable Constant Contact Force.Cyborg and bionic systems (Washington, D.C.) · 2025Article
- Reliability and reference values for diaphragmatic excursion, thickness, and thickening fraction and quadriceps femoris muscle thickness in full-term newborns evaluated by ultrasound.European journal of pediatrics · 2024Observational
- Thoracic manifestations and respiratory function alterations in axial spondyloarthritis and newest possibilities of ultrasound to detect changes in diaphragm-a narrative review.Journal of thoracic disease · 2024Review
- Diaphragm Ultrasound in Different Clinical Scenarios: A Review with a Focus on Older Patients.Geriatrics (Basel, Switzerland) · 2024Review
- Ultrasonographic reliability and repeatability of simultaneous bilateral assessment of diaphragm muscle thickness during normal breathing.Quantitative imaging in medicine and surgery · 2023Article
- Sonographic follow-up of diaphragm function in COVID-19: an exploratory study.ERJ open research · 2023Article
- Evaluation of diaphragm functions with diaphragm ultrasound and pulmonary function tests in individuals with Friedreich's ataxia.Turkish journal of medical sciences · 2023Article
- Intra-Rater Reliability of Shear Wave Elastography for the Quantification of Respiratory Muscles in Adolescent Athletes.Sensors (Basel, Switzerland) · 2022Article
- EXpert consensus On Diaphragm UltraSonography in the critically ill (EXODUS): a Delphi consensus statement on the measurement of diaphragm ultrasound-derived parameters in a critical care setting.Critical care (London, England) · 2022Article
- Diaphragm ultrasound to stratify COVID-19 patients in the emergency department?Journal of clinical ultrasound : JCU · 2022Article
- Ultrasound variations of diaphragm activity between prone position versus supine position in ventilated patients: a cross-sectional comparative study.Journal of ultrasound · 2021Article
- The role of extradiaphragmatic muscles' ultrasound on the diagnosis and follow-up of diaphragmatic dysfunction associated with cervical septic arthritis: A case report and literature review.Saudi journal of anaesthesiaArticle
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeWe have focused on the two-dimensional (B-mode) and the time-motion (M-mode) analysis of the zone of apposition to determine the reliability of diaphragm ultrasonography in the clinical environment.
methodsTen healthy volunteers were enrolled and studied by three operators with different skills in ultrasonography. For every volunteer, each operator acquired three images of the diaphragm for each side, both in B-mode and in M-mode. Then a fourth operator calculated the thickening fraction (TF), by means of the formula TF = (TEI - TEE)/TEE (TEI is the thickness at end inspiration and TEE the thickness at end expiration). Afterwards, intraclass correlation coefficients (ICCs) were computed on TF to establish reproducibility and repeatability both in the B- and M-modes. A Coefficient of Repeatability or repeatability (CR) ≤ 0.3 was considered acceptable.
resultsBoth B-mode (CRs 0.16-0.26) and M-mode (CRs 0.10-0.15) were sufficiently repeatable to assess TF, except for the less experienced operator (CRs B-Mode 0.20-0.32). Reproducibility was moderate to good between operators with CRs much narrower for the M-Mode (0.13-0.14).
conclusionsThe results of our study have shown that diaphragm ultrasound is repeatable and reproducible when carried out by a radiologist or an intensivist with a basic curriculum in ultrasonography. The method is more accurate when using the M-mode for less experienced operators, and in this case, repeatability and reproducibility are not sufficient to make clinical decisions. No TF value lower than 36% was obtained using both techniques. This suggests the existence of a cut-off value that could be used as an initial tool to discriminate healthy subjects from those affected by diaphragmatic dysfunction. CLINICAL
trial registrationEUDRACT 2015-004635-12.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.