Evidence map›Paper›PMID 32358562›Full record

ReviewNature reviews. Urology2020

Harnessing the potential of multimodal radiotherapy in prostate cancer.

Yiannis Philippou, Hanna Sjoberg, Alastair D Lamb, Philip Camilleri, Richard J Bryant

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Urology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.0field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 24 citations in OpenAlex.

  1. Review
  2. Synergistic potential and challenges of immunotherapy combined with radiotherapy in metastatic castration-resistant prostate cancer: a review of mechanisms and clinical advances.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Review
  3. Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. Synthesis of Multifunctional MnSensors (Basel, Switzerland) · 2023
    Article
  9. Article
  10. Synergistic effects of radiotherapy and targeted immunotherapy in improving tumor treatment efficacy: a review.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2022
    Review
  11. Review
  12. Article
  13. Circular RNA-regulated autophagy is involved in cancer progression.Frontiers in cell and developmental biology · 2022
    Review
  14. Cell death in pancreatic cancer: from pathogenesis to therapy.Nature reviews. Gastroenterology & hepatology · 2021
    Review
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Yiannis PhilippouCRUK/MRC Oxford Institute for Radiation Oncology, University of Oxford, Headington, Oxford, UK.
Hanna SjobergNuffield Department of Surgical Sciences, University of Oxford, Headington, Oxford, UK.ORCID 0000-0003-1948-6779
Alastair D LambNuffield Department of Surgical Sciences, University of Oxford, Headington, Oxford, UK.
Philip CamilleriOxford Department of Clinical Oncology, Churchill Hospital Cancer Centre, Oxford University Hospitals NHS Foundation Trust, Headington, Oxford, UK.ORCID 0000-0002-2677-5627
Richard J BryantCRUK/MRC Oxford Institute for Radiation Oncology, University of Oxford, Headington, Oxford, UK. richard.bryant@nds.ox.ac.uk.ORCID 0000-0002-8330-9251
Nuffield Orthopaedic Centre · GBChurchill Hospital · GB

Funding

Cancer Research UK 22748Cancer Research UK 25812
6 · The paper itself

Abstract

Radiotherapy in combination with androgen deprivation therapy (ADT) is a standard treatment option for men with localized and locally advanced prostate cancer. However, emerging clinical evidence suggests that radiotherapy can be incorporated into multimodality therapy regimens beyond ADT, in combinations that include chemotherapy, radiosensitizing agents, immunotherapy and surgery for the treatment of men with localized and locally advanced prostate cancer, and those with oligometastatic disease, in whom the low metastatic burden in particular might be treatable with these combinations. This multimodal approach is increasingly recognized as offering considerable clinical benefit, such as increased antitumour effects and improved survival. Thus, radiotherapy is becoming a key component of multimodal therapy for many stages of prostate cancer, particularly oligometastatic disease.

Indexed as

Combined Modality TherapyHumansMaleProstatic NeoplasmsRadiotherapy

Identifiers

PMID32358562
OpenAlexW3021633275

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.