Evidence map›Paper›PMID 32358503›Full record

ArticleNature communications2020

SYNERGISTIC ON AUXIN AND CYTOKININ 1 positively regulates growth and attenuates soil pathogen resistance.

Andrej Hurný, Candela Cuesta, Nicola Cavallari, Krisztina Ötvös, Jerome Duclercq, Ladislav Dokládal, Juan Carlos Montesinos, Marçal Gallemí, Hana Semerádová, Thomas Rauter and 12 more

Abstract read
In one paragraph

Article in Nature communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Article
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  5. Induction of Bioactive Secondary Metabolites inPlant-environment interactions (Hoboken, N.J.) · 2025
    Article
  6. Article
  7. Review
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  11. Article
  12. Article
  13. Review
  14. Article
  15. Review
  16. Review
  17. Plants (Basel, Switzerland) · 2022
    Article
  18. Review
  19. Auxin Interactions with Other Hormones in Plant Development.Cold Spring Harbor perspectives in biology · 2021
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Andrej HurnýInstitute of Science and Technology, Klosterneuburg, Austria.
Candela Cuesta *Institute of Science and Technology, Klosterneuburg, Austria.ORCID http://orcid.org/0000-0003-1923-2410
Nicola Cavallari *Institute of Science and Technology, Klosterneuburg, Austria.
Krisztina ÖtvösInstitute of Science and Technology, Klosterneuburg, Austria.
Jerome DuclercqUnité 'Ecologie et Dynamique des Systèmes Anthropisés' (EDYSAN UMR CNRS 7058 CNRS), Université du Picardie Jules Verne, UFR des Sciences, Amiens, France.ORCID http://orcid.org/0000-0002-4419-0307
Ladislav DokládalInstitute of Biophysics, The Czech Academy of Sciences, Královopolská 135, 61265, Brno, Czech Republic.
Juan Carlos MontesinosInstitute of Science and Technology, Klosterneuburg, Austria.
Marçal GallemíInstitute of Science and Technology, Klosterneuburg, Austria.
Hana SemerádováInstitute of Science and Technology, Klosterneuburg, Austria.
Thomas RauterInstitute of Science and Technology, Klosterneuburg, Austria.
Irene StenzelDepartment of Cellular Biochemistry, Institute for Biochemistry and Biotechnology, Martin-Luther-University Halle-Wittenberg, Halle, Germany.
Geert PersiauDepartment of Plant Biotechnology and Bioinformatics, Ghent University, Ghent, Belgium.
Freia BenadeInstitut für Botanik, Technische Universität Dresden, Dresden, Germany.
Rishikesh BhalearoUmeå Plant Science Centre, Department of Forest Genetics and Plant Physiology, Swedish University of Agricultural Sciences, S-901 83, Umeå, Sweden.
Eva SýkorováInstitute of Biophysics, The Czech Academy of Sciences, Královopolská 135, 61265, Brno, Czech Republic.ORCID http://orcid.org/0000-0002-4048-034X
András GorzsásDepartment of Chemistry, Umeå University, Linnaeus väg 6, SE-901 87, Umeå, Sweden.ORCID http://orcid.org/0000-0002-2298-8844
Julien SechetInstitut Jean-Pierre Bourgin, INRAE, AgroParisTech, Université Paris-Saclay, 78000, Versailles, France.ORCID http://orcid.org/0000-0001-8398-4743
Gregory MouilleInstitut Jean-Pierre Bourgin, INRAE, AgroParisTech, Université Paris-Saclay, 78000, Versailles, France.
Ingo HeilmannDepartment of Cellular Biochemistry, Institute for Biochemistry and Biotechnology, Martin-Luther-University Halle-Wittenberg, Halle, Germany.ORCID http://orcid.org/0000-0002-2324-1849
Geert De JaegerDepartment of Plant Biotechnology and Bioinformatics, Ghent University, Ghent, Belgium.
Jutta Ludwig-MüllerInstitut für Botanik, Technische Universität Dresden, Dresden, Germany.ORCID http://orcid.org/0000-0002-9403-5153
Eva BenkováInstitute of Science and Technology, Klosterneuburg, Austria. eva.benkova@ist.ac.at.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Plants as non-mobile organisms constantly integrate varying environmental signals to flexibly adapt their growth and development. Local fluctuations in water and nutrient availability, sudden changes in temperature or other abiotic and biotic stresses can trigger changes in the growth of plant organs. Multiple mutually interconnected hormonal signaling cascades act as essential endogenous translators of these exogenous signals in the adaptive responses of plants. Although the molecular backbones of hormone transduction pathways have been identified, the mechanisms underlying their interactions are largely unknown. Here, using genome wide transcriptome profiling we identify an auxin and cytokinin cross-talk component; SYNERGISTIC ON AUXIN AND CYTOKININ 1 (SYAC1), whose expression in roots is strictly dependent on both of these hormonal pathways. We show that SYAC1 is a regulator of secretory pathway, whose enhanced activity interferes with deposition of cell wall components and can fine-tune organ growth and sensitivity to soil pathogens.

Indexed as

ArabidopsisArabidopsis ProteinsCell WallCytokininsDisease ResistanceEndosomesGene Expression ProfilingGene Expression Regulation, PlantGolgi ApparatusIndoleacetic AcidsMembrane ProteinsPlant Growth RegulatorsPlant RootsPlants, Genetically ModifiedPlasmodiophoridaSecretory PathwayArabidopsis ProteinsAT2G18840 protein, ArabidopsisAT4G30260 protein, ArabidopsisCytokininsECHIDNA protein, ArabidopsisIndoleacetic AcidsMembrane ProteinsPlant Growth RegulatorsSoilSYAC1 protein, ArabidopsisVesicular Transport Proteins

Identifiers

PMID32358503
PMCPMC7195429

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.