Evidence map›Paper›PMID 32358232›Full record

ReviewASAIO journal (American Society for Artificial Internal Organs : 1992)2020

Advanced Pulmonary and Cardiac Support of COVID-19 Patients: Emerging Recommendations From ASAIO-A "Living Working Document".

Keshava Rajagopal, Steven P Keller, Bindu Akkanti, Christian Bime, Pranav Loyalka, Faisal H Cheema, Joseph B Zwischenberger, Aly El Banayosy, Federico Pappalardo, Mark S Slaughter and 1 more

Open access · greenAbstract readReview
In one paragraph

Review in ASAIO journal (American Society for Artificial Internal Organs : 1992), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 2 pooled it
6.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 71 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Observational
  5. Review
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Renal Considerations in COVID-19: Biology, Pathology, and Pathophysiology.ASAIO journal (American Society for Artificial Internal Organs : 1992) · 2021
    Article
  14. Review
  15. Article
  16. Review
  17. Observational
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 2 countries.

Keshava RajagopalFrom the Departments of Clinical and Biomedical Sciences, University of Houston College of Medicine, Houston, TX.
Steven P KellerDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA.
Bindu AkkantiDivision of Pulmonary and Critical Care Medicine, Department of Medicine, McGovern Medical School, University of Texas-Houston, Houston, TX.
Christian BimeDivision of Pulmonary and Critical Care Medicine, Department of Medicine, University of Arizona College of Medicine - Tucson and Banner Health, Tucson, AZ.
Pranav LoyalkaHouston Heart, HCA Houston Healthcare, Houston, TX.
Faisal H CheemaFrom the Departments of Clinical and Biomedical Sciences, University of Houston College of Medicine, Houston, TX.
Joseph B ZwischenbergerDepartment of Surgery, University of Kentucky College of Medicine and Medical Center, Lexington, KY.
Aly El BanayosyNazih Zuhdi Transplant Institute, Integris Baptist Medical Center, Oklahoma City, OK.
Federico PappalardoVita-Salute San Raffaele University, Milan, Italy.
Mark S SlaughterDepartment of Cardiovascular and Thoracic Surgery, University of Louisville School of Medicine and Jewish Hospital, Louisville, KY.
Marvin J SlepianDepartment of Cardiovascular and Thoracic Surgery, University of Louisville School of Medicine and Jewish Hospital, Louisville, KY.
University of Houston · USBrigham and Women's Hospital · USUniversity of Arizona · USUniversity of Kentucky · USUniversity of Louisville · USVita-Salute San Raffaele University · IT

Funding

SELPLG as a candidate gene in Acute Respiratory Distress SyndromeK08HL141623 · NHLBI · UNIVERSITY OF ARIZONA · PI BIME, CHRISTIAN · 2018 to 2022
$863k
Functional restoration of ventriculo-arterial coupling in cardiogenic shock via dual mechanical supportK08HL143342 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI KELLER, STEVEN PAUL · 2018 to 2023
$853k
NHLBI NIH HHS K08 HL141623NHLBI NIH HHS K08 HL143342
6 · The paper itself

Abstract

The severe acute respiratory syndrome (SARS)-CoV-2 is an emerging viral pathogen responsible for the global coronavirus disease 2019 (COVID)-19 pandemic resulting in significant human morbidity and mortality. Based on preliminary clinical reports, hypoxic respiratory failure complicated by acute respiratory distress syndrome is the leading cause of death. Further, septic shock, late-onset cardiac dysfunction, and multiorgan system failure are also described as contributors to overall mortality. Although extracorporeal membrane oxygenation and other modalities of mechanical cardiopulmonary support are increasingly being utilized in the treatment of respiratory and circulatory failure refractory to conventional management, their role and efficacy as support modalities in the present pandemic are unclear. We review the rapidly changing epidemiology, pathophysiology, emerging therapy, and clinical outcomes of COVID-19; and based on these data and previous experience with artificial cardiopulmonary support strategies, particularly in the setting of infectious diseases, provide consensus recommendations from ASAIO. Of note, this is a "living document," which will be updated periodically, as additional information and understanding emerges.

Indexed as

BetacoronavirusAnimalsCoronavirus InfectionsCOVID-19Extracorporeal Membrane OxygenationHeart DiseasesHumansPandemicsPneumonia, ViralRespiratory InsufficiencySARS-CoV-2

Identifiers

PMID32358232
PMCPMC7217129
OpenAlexW3023532622

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.