ArticleProceedings of the National Academy of Sciences of the United States of America2020
Increased variability but intact integration during visual navigation in Autism Spectrum Disorder.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 2 of them syntheses that pooled it.
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Who cites it
31 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Minimal Differences in Auditory and Visual Oddball Tasks in Autism: A Systematic Review and Meta-Analysis.Journal of autism and developmental disorders · 2026Pooled it
- Action execution and observation in autistic adults: A systematic review of fMRI studies.Autism research : official journal of the International Society for Autism Research · 2025Pooled it
- Neurophysiological dynamics related to perception, action, and language in schizophrenia.Science advances · 2026Article
- A Reliable Effect of Alexithymia, but Not Autism, on Placebo Hypoalgesia.Autism : the international journal of research and practice · 2026Article
- Diminished Signal-to-Noise Ratio Disrupts Somatosensory Population Encoding and Drives Tactile Hyposensitivity in the Fmr1Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- From spatial to social competence: The association between spatial ability and prosocial behaviour in childhood.The British journal of developmental psychology · 2026Article
- Behavioural and neuronal insights into multisensory combination of unpracticed cues.bioRxiv : the preprint server for biology · 2025Article
- A common computational and neural anomaly across mouse models of autism.Nature neuroscience · 2025Article
- Neural mechanisms of spatial navigation in ASD and TD children: insights from EEG microstate and functional connectivity analysis.Frontiers in psychiatry · 2025Article
- Autism spectrum disorder variation as a computational trade-off via dynamic range of neuronal population responses.Nature neuroscience · 2024Article
- Erroneous predictive coding across brain hierarchies in a non-human primate model of autism spectrum disorder.Communications biology · 2024Article
- Context-invariant beliefs are supported by dynamic reconfiguration of single unit functional connectivity in prefrontal cortex of male macaques.Nature communications · 2024Article
- Article
- Multisensory Integration and Causal Inference in Typical and Atypical Populations.Advances in experimental medicine and biology · 2024Review
- Self-motion perception and sequential decision-making: where are we heading?Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023Review
- Causal inference during closed-loop navigation: parsing of self- and object-motion.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023Article
- Testing predictive coding theories of autism spectrum disorder using models of active inference.PLoS computational biology · 2023Article
- Context-invariant beliefs are supported by dynamic reconfiguration of single unit functional connectivity in prefrontal cortex.bioRxiv : the preprint server for biology · 2023Article
- A theory of autism bridging across levels of description.Trends in cognitive sciences · 2023Review
- Causal inference during closed-loop navigation: parsing of self- and object-motion.bioRxiv : the preprint server for biology · 2023Article
Corrections and comments
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4 authors.
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Abstract
Autism Spectrum Disorder (ASD) is a common neurodevelopmental disturbance afflicting a variety of functions. The recent computational focus suggesting aberrant Bayesian inference in ASD has yielded promising but conflicting results in attempting to explain a wide variety of phenotypes by canonical computations. Here, we used a naturalistic visual path integration task that combines continuous action with active sensing and allows tracking of subjects' dynamic belief states. Both groups showed a previously documented bias pattern by overshooting the radial distance and angular eccentricity of targets. For both control and ASD groups, these errors were driven by misestimated velocity signals due to a nonuniform speed prior rather than imperfect integration. We tracked participants' beliefs and found no difference in the speed prior, but there was heightened variability in the ASD group. Both end point variance and trajectory irregularities correlated with ASD symptom severity. With feedback, variance was reduced, and ASD performance approached that of controls. These findings highlight the need for both more naturalistic tasks and a broader computational perspective to understand the ASD phenotype and pathology.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.