Evidence map›Paper›PMID 32357961›Full record

ArticleGenetics2020

A Light-Inducible Strain for Genome-Wide Histone Turnover Profiling in

William K Storck, Sabrina Z Abdulla, Michael R Rountree, Vincent T Bicocca, Eric U Selker

Open access · bronzeAbstract read
In one paragraph

Article in Genetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Article
  3. Histone deacetylation and cytosine methylation compartmentalize heterochromatic regions in the genome organization ofProceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

William K StorckInstitute of Molecular Biology, University of Oregon, Eugene, Oregon 97403.ORCID 0000-0002-8100-9191
Sabrina Z AbdullaInstitute of Molecular Biology, University of Oregon, Eugene, Oregon 97403.
Michael R RountreeInstitute of Molecular Biology, University of Oregon, Eugene, Oregon 97403.ORCID 0000-0003-2371-6389
Vincent T BicoccaInstitute of Molecular Biology, University of Oregon, Eugene, Oregon 97403.ORCID 0000-0002-5702-4586
Eric U SelkerInstitute of Molecular Biology, University of Oregon, Eugene, Oregon 97403 selker@uoregon.edu.ORCID 0000-0001-6465-0094
University of Oregon · USUniversity of Illinois Urbana-Champaign · US

Funding

Graduate Training in Genetics Administrative Supplement - Career Curriculum DevelopmentT32GM007413 · NIGMS · UNIVERSITY OF OREGON · PI GUILLEMIN, KAREN J · 1985 to 2022
$7.8M
Genetic Aspects of DNA MethylationR37GM035690 · NIGMS · UNIVERSITY OF OREGON · PI SELKER, ERIC U. · 2003 to 2012
$5.2M
GENETIC ASPECTS OF DNA METHYLATIONR01GM035690 · NIGMS · UNIVERSITY OF OREGON · PI SELKER, ERIC U. · 1986 to 2016
$3.3M
Control and function of heterochromatin in Neurospora crassaR35GM127142 · NIGMS · UNIVERSITY OF OREGON · PI SELKER, ERIC U. · 2018 to 2022
$2.6M
Characterization of SET-3 and its role in DNA methylationF32CA180468 · NCI · UNIVERSITY OF OREGON · PI BICOCCA, VINCENT T. · 2013 to 2016
$161k
NCI NIH HHS F32 CA180468NIGMS NIH HHS R01 GM035690NIGMS NIH HHS R35 GM127142NIGMS NIH HHS R37 GM035690NIGMS NIH HHS T32 GM007413
6 · The paper itself

Abstract

In chromatin, nucleosomes are composed of ∼146 bp of DNA wrapped around a histone octamer, and are highly dynamic structures subject to remodeling and exchange. Histone turnover has previously been implicated in various processes including the regulation of chromatin accessibility, segregation of chromatin domains, and dilution of histone marks. Histones in different chromatin environments may turnover at different rates, possibly with functional consequences.

Indexed as

Histone CodeLightChromatinFungal ProteinsGenes, ReporterGenetic EngineeringHistonesNeurospora crassaOptogeneticsPromoter Regions, GeneticChromatinFungal ProteinsHistoneschromatin profilinghistone exchangelight inductionNeurospora crassa heterochromatin

Identifiers

PMID32357961
PMCPMC7337079
OpenAlexW3022141125

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.