Evidence map›Paper›PMID 32357943›Full record

Observational studyBMC public health2020

Barriers and facilitators to dissemination and adoption of precision medicine among Hispanics/Latinos.

Juan R Canedo, Consuelo H Wilkins, Nicole Senft, Araceli Romero, Kemberlee Bonnet, David Schlundt

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in BMC public health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 46 citations in OpenAlex.

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  20. Barriers and Facilitators to Genetic Education, Risk Assessment, and Testing: Considerations on Advancing Equitable Genetics Care.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Juan R CanedoSchool of Graduate Studies and Research, Meharry Medical College, Nashville, TN, USA. juan.r.canedo@vumc.org.
Consuelo H WilkinsVanderbilt University Medical Center, Nashville, TN, USA.
Nicole SenftVanderbilt University Medical Center, Nashville, TN, USA.
Araceli RomeroProgreso Community Center, Nashville, TN, USA.
Kemberlee BonnetDepartment of Psychology, Vanderbilt University, Nashville, TN, USA.
David SchlundtDepartment of Psychology, Vanderbilt University, Nashville, TN, USA.
Vanderbilt University · USVanderbilt University Medical Center · USMeharry Medical College · US

Funding

The Vanderbilt Institute for Clinical and Translational Research (VICTR)UL1TR000445 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BERNARD, GORDON RAPHAEL · 2012 to 2016
$41.4M
Technologies and Resources CoreU54MD007593 · NIMHD · MEHARRY MEDICAL COLLEGE · PI ADUNYAH, SAMUEL EVANS · 2012 to 2018
$24.7M
Training and Mentoring CoreU54MD010722 · NIMHD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI WILKINS, CONSUELO HOPKINS · 2016 to 2020
$11.9M
Learning Health System training program: PROgRESS--Patient/ pRactice Outcomes and Research in Effectiveness and Systems ScienceT32HS026122 · AHRQ · VANDERBILT UNIVERSITY MEDICAL CENTER · PI GRIJALVA, CARLOS G, ROUMIE, CHRISTIANNE L. · 2018 to 2024
$3.5M
Agency for Healthcare Research and Quality T32HS26122AHRQ HHS T32 HS026122NCATS NIH HHS UL1 TR000445NIH HHS U54MD007593NIH HHS U54MD010722NIH HHS UL1-TR000445NIMHD NIH HHS U54 MD007593NIMHD NIH HHS U54 MD010722
6 · The paper itself

Abstract

backgroundWith the rapid advances in gene technologies in recent years, the potential benefits of precision medicine (PM) may spread unevenly to disadvantaged populations, such as Hispanics/Latinos. The objective of this study was to explore patient-level barriers and facilitators to dissemination and adoption of PM among Hispanics/Latinos, including knowledge and awareness.

methodsSelf-identified Hispanics/Latinos from diverse countries in Latin America (N = 41) participated in the study. Using a cross-sectional observational qualitative research design, six focus groups and a demographic questionnaire were collected in English and Spanish. Qualitative content analysis was utilized to code the transcripts and identify emerging themes.

resultsHispanics/Latinos never heard of and had no knowledge about PM. Barriers to dissemination and adoption of PM included lack of health insurance, financial burden, participants' immigration status, distrust of government, limited English proficiency, low literacy levels, cultural norms, fear about genetic testing results, lack of transportation, newness of PM, and lack of information about PM. Facilitators included family support; information provided in Spanish; use of plain language and graphics; assistance programs for uninsured; trust in physicians, healthcare staff, well-known hospitals, academic institutions, and health care providers and community organization as sources of reliable information; personal motivation, and altruism or societal benefit.

conclusionsCulturally-and linguistically-tailored, low-literacy educational material about PM should be created in English and Spanish. Future research should examine provider-level and system-level barriers and facilitators to implementation and adoption of PM among Hispanic/Latino patients.

Indexed as

Communication BarriersHealth Knowledge, Attitudes, PracticeAdolescentAdultAgedCross-Sectional StudiesFemaleFocus GroupsHispanic or LatinoHumansLatin AmericaMaleMiddle AgedPrecision MedicineQualitative ResearchYoung AdultAdoptionAwarenessBarriersDisparitiesDisseminationFacilitatorsHispanicsKnowledgeLatinosPrecision medicine

Identifiers

PMID32357943
PMCPMC7195743
OpenAlexW3022879161

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.